Product Description
Aldehyde-PEG-Aldehyde (ALD-PEG-ALD) is a linear bifunctional crosslinking PEG reagent with one aldehyde聽at both ends of PEG. 聽聽Aldehyde reacts with amine and N-terminal of peptide and protein to form an imine containing a C=N double bond, which can be further reduced to a more stable C-N bond.聽聽PEG aldehyde or ketone derivatives can be used in reversible PEGylation through its reaction with hydrazine or hydrazide forming a hydrolytic acyl hydrazone linkage.
nanosoftpolymers/DSPE-PEG-Biotin/DSPE-PEG-BIO/2356-2000-500 mg/500 mg
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2020-07-06 16:50
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公司介绍
DSPE-PEG-Biotin
1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[biotinyl(polyethylene glycol)] (DSPE-PEG-BIO)
Description
Additional information
Product Description
DSPE-PEG-Biotin (DSPE-PEG-BIO) is a linear heterobifunctional PEGylation reagent with a DSPE phospholipid and a biotin. It is a useful self-assembling reagent to prepare grafted or PEGylated liposome or micelle while also providing an biotin group for binding to avidin or streptavidin.
It is often used in targeted drug delivery with the lipid bilayer to improve drug solubility, the PEG to provide stealth property, extend circulation half-life and reduce non-specific protein binding or cell adhesion, and the biotin group to non-covalently bind to targeting molecules including antibody, aptamer, protein, and peptide.
Additional information
Molecular size
1000, 2000, 3400, 5000
Package size
100 mg, 500 mg, 1g
