MedKooCat#:406326
Name:PIK-90
CAS#:677338-12-4
ChemicalFormula:C18H17N5O3
ExactMass:351.13314
MolecularWeight:351.36
ElementalAnalysis:C,61.53;H,4.88;N,19.93;O,13.66
Synonym:PIK90;PIK90;PIK90.
IUPAC/ChemicalName:N-(7,8-dimethoxy-2,3-dihydroimidazo[1,2-c]quinazolin-5-yl)nicotinamide
InChiKey:ZJAVHOMVDCMAMF-UHFFFAOYSA-N
InChiCode:InChI=1S/C18H17N5O3/c1-25-13-6-5-12-14(15(13)26-2)21-18(23-9-8-20-16(12)23)22-17(24)11-4-3-7-19-10-11/h4-7,10H,8-9H2,1-2H3,(H,21,22,24)
SMILESCode:O=C(NC1=NC2=C(C=CC(OC)=C2OC)C3=NCCN13)C4=CN=CC=C4
TechnicalData
AdditionalInformation
References
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4:FanQW,ChengCK,NicolaidesTP,HackettCS,KnightZA,ShokatKM,WeissWA.Adualphosphoinositide-3-kinasealpha/mTORinhibitorcooperateswithblockadeofepidermalgrowthfactorreceptorinPTEN-mutantglioma.CancerRes.2007Sep1;67(17):7960-5.PubMedPMID:17804702;PubMedCentralPMCID:PMC2597547.
