MedKoo Cat#: 205612
Name: RG7304
CAS#: 213406-50-9
Chemical Formula: C12H12N4O
Exact Mass: 228.1011
Molecular Weight: 228.255
Elemental Analysis: C, 63.15; H, 5.30; N, 24.55; O, 7.01
Synonym: CKI27; CK127; CK 127; RG7304; RG7304; RG 7304 R7304.
IUPAC/Chemical Name: (E)-5-(2-benzylidene-1-methylhydrazinyl)pyridazin-3(2H)-one
SMILES Code: CN(C(C=NN1)=CC1=O)/N=C/C2=CC=CC=C2
Technical Data
Additional Information
CKI 27 (RG7304) is a MEK inhibitor currently in clinical trials.
References
1: Chiou GC, Xuan B, Yamasaki T, Okawara T. Anti-inflammation and
antifibroblastic actions of interleukin-1 blockers. J Ocul Pharmacol Ther. 1998
Aug;14(4):375-88. PubMed PMID: 9715441.
