Description | MTT,ayellowtetrazole,isreducedtopurpleformazaninlivingcells,andusedforassessingcellmetabolicactivity. |
---|---|
InVitro | MTTisusedinconjunctionwithrhodamineBtomeasuremitochondrialmembranepotential.MTT-formazanisgeneratedinmitochondriaactsasafluorescencequencherforrhodaminethatdistributesacrossmembranesofviablecellsaccordingtomembranepotential.IntheabsenceofmPMS,cellularreductionofMTTisstrong.MTTismembrane-impermeablewhenincorporatedintolargeunilamellarliposomes,andthereforeitistakenupbycellsviaendocytosis[1]. |
ClinicalTrial | ViewMoreCollapse |
References |
|
PreparingStockSolutions |
Pleaserefertothesolubilityinformationtoselecttheappropriatesolvent. | ||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
References |
|
MolecularWeight | 414.32 | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Formula | C₁₈H₁₆BrN₅S | ||||||||||||
CASNo. | 298-93-1 | ||||||||||||
Storage |
| ||||||||||||
Shipping | RoomtemperatureincontinentalUS;mayvaryelsewhere | ||||||||||||
Solvent&Solubility | DMSO:≥32mg/mL;H2O:0.88mg/mL(Needultrasonicandwarming) *"<1 mg/ml"="" means="" slightly="" soluble="" or="" insoluble.="" "≥"="" means="" soluble,="" but="" saturation="">1> Purity:99.59%
|