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蚂蚁淘在线 / 品牌中心 / MCE / Medchemexpress/Pepstatin(Synonyms: Pepstatin A; Isovaleryl-Val-Val-Sta-Ala-Sta-OH)/HY-P0018/100mg

Medchemexpress/Pepstatin(Synonyms: Pepstatin A; Isovaleryl-Val-Val-Sta-Ala-Sta-OH)/HY-P0018/100mg

价格
￥1200.00
货号：HY-P0018-10mg
浏览量：127
品牌：MCE
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商品描述
Pepstatinisapotentinhibitorofaspartylproteases,andinhibitstheasparticproteasescathepsinD,pepsin,andrenin.
Description

Pepstatinisapotentinhibitorofaspartylproteases,andinhibitstheasparticproteasescathepsinD,pepsin,andrenin.

InVivo

Alowdoseofpepstatinshowsaninhibitionofedemaformation,andintraperitonealinjectionof1.25mg/kgofpepstatincausesa30%inhibitionwithaaverylowtoxicity[1].PepstatinincreasesLC3-IIlevels,whileitisrevertedby3-methyladenine(3-MA)[2].

References

  • [1].UmezawaH,etal.Pepstatin,anewpepsininhibitorproducedbyActinomycetes.JAntibiot(Tokyo).1970May;23(5):259-62.

    [2].RaquelT.Lima,etal.ModulationofAutophagybyaThioxanthoneDecreasestheViABIlityofMelanomaCells.Molecules2016,21(10),1343

PreparingStockSolutions
ConcentrationVolumeMass1mg5mg10mg
1mM1.4580mL7.2898mL14.5796mL
5mM0.2916mL1.4580mL2.9159mL
10mM0.1458mL0.7290mL1.4580mL
Pleaserefertothesolubilityinformationtoselecttheappropriatesolvent.
References

  • [1].UmezawaH,etal.Pepstatin,anewpepsininhibitorproducedbyActinomycetes.JAntibiot(Tokyo).1970May;23(5):259-62.

    [2].RaquelT.Lima,etal.ModulationofAutophagybyaThioxanthoneDecreasestheViabilityofMelanomaCells.Molecules2016,21(10),1343

MolecularWeight

685.89

Formula

C₃₄H₆₃N₅O₉

CASNo.

26305-03-3

Storage
Powder-80°C2years
 -20°C1year
Insolvent-80°C6months
 -20°C1month
Shipping

RoomtemperatureincontinentalUS;mayvaryelsewhere

Solvent&Solubility

DMSO:≥25mg/mL

*"<1 mg/ml"="" means="" slightly="" soluble="" or="" insoluble.="" "≥"="" means="" soluble,="" but="" saturation="">

Purity:98.45%