| Description | Ademetionine(S-adenosyl-l-methionine;SAMe)isanaturally-occurringsubstancewhichisamajorsourceofmethylgroupsinthebrain.Target:OthersS-adenosyl-l-methionine(SAMe)isanaturally-occurringsubstancewhichisamajorsourceofmethylgroupsinthebrain.TheefficacyofSAMeintreatingdepressivesyndromesanddisordersissuperiorwiththatofplaceboandcomparabletothatofstandardtricyclicantidepressants.SinceSAMeisanaturallyoccurringcompoundwithrelativelyfewside-effects,itisapotentiallyimportanttreatmentfordepression[1].S-adenosylmethionine(SAMe)isadietarysupplementusedinthemanagementofosteoarthritis(OA)symptoms.StudiesevaluatingSAMeinthemanagementofOAhavebeenlimitedtoNonSteroidalAnti-inflammatoryDrugs(NSAIDs)forcomparison.ThepresentstudycomparestheeffectivenessofSAMetoacyclooxygenase-2(COX-2)inhibitor(celecoxib)forpaincontrol,functionalimprovementandtodecreasesideeffectsinpeoplewithosteoarthritisoftheknee[2]. |
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| ClinicalTrial | ViewMoreCollapse |
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| MolecularWeight | 398.44 | ||||||||||||
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| Formula | C₁₅H₂₂N₆O₅S | ||||||||||||
| CASNo. | 29908-03-0 | ||||||||||||
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| Shipping | RoomtemperatureincontinentalUS;mayvaryelsewhere | ||||||||||||
| Solvent&Solubility | H2O:≥43mg/mL;DMSO:≥100mg/mL(Needultrasonic) *"<1 mg/ml"="" means="" slightly="" soluble="" or="" insoluble.="" "≥"="" means="" soluble,="" but="" saturation=""> Purity:>98.0% |
