Catalog#:1806

ScientificName:L-threo-Sphingosine

CommonName:L-threo-Sphingosine,C18chain

EmpiricalFormula:C₁₈H₃₇NO₂

CAS#25695-95-8

SDSViewSafetyDataSheet

DataSheet:ViewDataSheet

FormulaWeight:299

Unit:10mg

Solvent:none

Source:synthetic

Purity:98+%

AnalyticalMethods:TLC,GC

Solubility:ethanol,methanol,chloroform,DMSO

PhysicalAppearance:solid

Storage:-20°C

DryIce:No

Hazardous:No

LiteratureReferences:
1.Y.Hannunetal.“StereoselectivityofInductionoftheRetinoblastomaGeneProduct(pRb)DephosphorylationbyD-erythro-SphingosineSupportsaRoleforpRbinGrowthSuppressionbySphingosine”Biochemistry,vol.34pp.1885-1892,1995
2.C.Kingetal.“SphingosineIsaNovelActivatorof3-Phosphoinositide-dependentKinase1”TheJournalofBIOLOGicalChemistry,vol.275(24)pp.18108-18113,2000
3.S.Spiegeletal.“Stereospeci~cityofSp~ingosine-indu~eIdntracellularCalciumMobilizationandCellularProliferation”JournalofBiologicalChemistry,vol.269pp.17924-17930,1994
4.V.Stevensetal.“Structuralrequirementsforlong-chain(sphingoid)baseinhibitionofproteinkinaseCinvitroandforthecellulareffectsofthesecompounds”Biochemistry,vol.28,3138-3145,1989

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