Catalog#:2052

ScientificName:N-omega-CD₃-OctadecanoylmonosialogangliosideGM₃(NH₄⁺salt)

CommonName:N-CD₃-Stearoyl-GM₃

EmpiricalFormula:C₅₉H₁₀₅D₃N₂O₂₁•NH₃

SDSViewSafetyDataSheet

DataSheet:ViewDataSheet

FormulaWeight:1185+NH₃

Unit:250ug

Source:semisynthetic,bovinebuttermilk

Purity:98+%

AnalyticalMethods:TLC,identityconfirmedbyMS

Solubility:chloroform/methanol/water,2:1:0.1;formsmicellarsolutioninwater

PhysicalAppearance:solid

Storage:-20°C

DryIce:No

Hazardous:No

LiteratureReferences:
1.J.Gu,C.TifftandS.Soldin“SimultaneousquantificationofGM1andGM2gangliosidesbyisotopedilutiontandemmassspectrometry”ClinicalBiochemistry,Vol.41(6)pp.413-417,2008
2.L.Svennerholm,etal.(eds.),StructureandFunctionofGangliosides,NewYork,Plenum,1980
3.T.Kolter,R.Proia,K.Sandhoff“CombinatorialGangliosideBiosynthesis”J.Biol.Chem.,Vol.277:29,pp.25859-25862,2002
4.S.Birkle,G.Zeng,L.Gao,R.K.Yu,andJ.Aubry“Roleoftumor-associatedgangliosidesincancerprogression”Biochimie,Vol.85pp.455–463,2003
5.E.G.Bremer,J.Schlessinger,andS.Hakomori“Ganglioside-mediatedmodulationofcellgrowth.SpecificeffectsofGM3ontyrosinephosphorylationoftheepidermalgrowthfactorreceptor”J.Biol.Chem.,Vol.261pp.2434–2440,1986
6.T.Chung,H.Choi,Y.Lee,andC.Kim“MolecularmechanismfortranscriptionalactivationofgangliosideGM3synthaseanditsfunctionindifferentiationofHL-60cells”GlycoBIOLOGy,Vol.15:3,pp.233-244,2004

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