Catalog#:1755

ScientificName:D,L-erythro-PDMP

CommonName:D,L-erythro-1-Phenyl-2-decanoylamino-3-morpholino-1-propanol•HCl

EmpiricalFormula:C₂₃H₃₈N₂O₃•HCl

CAS#109760-77-2

SDSViewMaterialSafetyDataSheet

DataSheet:ViewDataSheet

FormulaWeight:427

Unit:100mg

Source:synthetic

Purity:98+%

AnalyticalMethods:TLC;identityconfirmedbyMS

Solubility:ethanol,methanol,chloroform,DMSO

PhysicalAppearance:solid

Storage:-20°C

DryIce:No

Hazardous:No

LiteratureReferences:
1.R.Vunnam,N.RADIn“Analogsofceramidethatinhibitglucocerebrosidesynthetaseinmousebrain”ChemPhysLipids,Vol.26(3)pp.265-278,1980
2.N.Radinetal.“EffectsofD-threo-PDMP,aninhibitorofglucosylceramidesynthetase,onexpressionofcellsurfaceglycolipidantigenandbindingtoadhesiveproteinsbyB16melanomacells”JournalofCellularPhysiology,Vol.141(3)pp.573–583,1989
3.N.Radinetal.“Effectofaninhibitorofglucosylceramidesynthesisonculturedrabbitskinfibroblasts”JournalofBiochemsitry,vol.108:4pp.525-530,1990
4.N.Radin,etal.“Structuralandstereochemicalstudiesofpotentinhibitorsofglucosylceramidesynthaseandtumorcellgrowth”JournalofLipidResearch,Vol.36pp.611-621,1995

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