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苏州工业园区生物纳米园A4#216
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4000-520-616 / 18915418616
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0512-67156496
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商品描述
StorageConditions:4-20C
pH:Varies
Conductance:Varies
Appearance:ClearSolutions
pH:Varies
Conductance:Varies
Appearance:ClearSolutions
Features
ThelatestscreenfromJanetNewman&Colleagues
96ofthemostproductiveconditionsintheProteinDataBank
Identicaltoatleast17%ofallPDBentries
Highlysimilartoatleast40%ofallPDBentries
Non-redundantsamplingofsuccessfulconditions
Commercialcrystallizationscreensoffermorethan15000crystallizationconditionsforreadyscreeningofnewcrystallizationtargets.However,notallconditionsarewell-representedintheProteinDataBankand,certainly,somehavebeenfarmoresuccessfulthanothers. TOP96wasgeneratedbycreatingtwodatabases-onefornon-redundantcommerciallyavailablecrystallizationconditionsandoneforuniquepairsofproteinsequenceswithcrystallizationconditionsreportedinREMARK280ofeachPDBentry. Bothstrictand"fuzzy"overlapsbetweenthetwosetswerecalculatedandthemostfrequentlyreportedcrystallizationconditionsidentified.
Theresult?Themostproductive96crystallizationconditionsthatcanbeextractedfromtheentirePDBarchiveandthebestplacetostartyourcrystallizationscreening.
Citations:
- FazioVJ,PeatTS&NewmanJ(2014).AdrunkensearchinCrystallizationSpace.ActaCryst.F70:1303