Description
PHT-427 is an inhibitor of PDK1 and Akt that exhibits anticancer chemotherapeutic activity, inhibiting tumor growth in animal models of breast cancer and non-small cell lung cancer (NSCLC).
PHT-427 is an inhibitor of PDK1 and Akt that exhibits anticancer chemotherapeutic activity, inhibiting tumor growth in animal models of breast cancer and non-small cell lung cancer (NSCLC).
Cas No. | 1191951-57-1 |
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Purity | ≥98% |
Formula | C20H31N3O2S2 |
Formula Wt. | 409.61 |
IUPAC Name | 4-dodecyl-N-(1,3,4-thiadiazol-2-yl)benzenesulfonamide |
Synonym | PHT427 |
Appearance | White Crystal Powder |
Store Temp | -20°C |
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Ship Temp | Ambient |
Info Sheet | P3076 Info Sheet PDF |
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Brochures | PI3K-Akt-mTORC Pathway Booklet |
Meuillet EJ, Zuohe S, Lemos R, et al. Molecular pharmacology and antitumor activity of PHT-427, a novel Akt/phosphatidylinositide-dependent protein kinase 1 pleckstrin homology domain inhibitor. Mol Cancer Ther. 2010 Mar;9(3):706-17. PMID: 20197390.
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