Description
PizotylineisastimulantthatactsasanantagoNISTat5-HT2Creceptorsandasapartialagonistat5-HT1Areceptors.Pizotylineisclinicallyusedtotreatmigraines,butalsoinhibitsdrug-inducedleverpressrespondingindrugdiscriminationmodels.
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4000-520-616 / 18915418616
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0512-67156496
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商品描述
ProductIDP3597
CasNo.5189-11-7
Purity≥98%
- Description
- ProductInfo
- ShippingandStorage
- Downloads
- References
ProductInfo
| CasNo. | 5189-11-7 |
|---|---|
| Purity | ≥98% |
| Formula | C19H21NS•C4H6O5 |
| FormulaWt. | 429.54 |
| ChemicalName | 4-(9,10-Dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thien-4ylidene)-1-methylpiperidine |
| IUPACName | 4-(4,5-dihydrobenzo[1,2]cyclohepta[3,4-b]thiophen-10-ylidene)-1-methylpiperidine;2-hydroxybutanedioicacid |
| Synonym | Pizotifen;Pizotifan;BC105 |
| MeltingPoint | 185-186°C(dec) |
| Solubility | Veryslightlysolubleinwater.Slightlysolubleinchloroformandethanol. |
| Appearance | Whiteoralmostwhitecrystallinepowder |
ShippingandStorage
| StoreTemp | Ambient |
|---|---|
| ShipTemp | Ambient |
Downloads
| InfoSheet | P3597InfoSheetPDF |
|---|
References
YoungR,KhoranaN,BondarevaT,etal.PizotylineeffectivelyattenuatesthestimuluseffectsofN-methyl-3,4-methylenedioxyamphetamine(MDMA).PharmacolBiochemBehav.2005Oct;82(2):404-10.PMID:16253319.
StrachanAT,LeiperJB,MaughanRJ.SEROtonin2CreceptorblockadeandThermoregulationduringexerciseintheheat.MedSciSportsExerc.2005Mar;37(3):389-94.PMID:15741836.
Newman-TancrediA,ConteC,ChaputC,etal.Agonistactivityofantimigrainedrugsatrecombinanthuman5-HT1Areceptors:potentialimplicationsforprophylacticandacutetherapy.NaunynSchmiedebergsArchPharmacol.1997Jun;355(6):682-8.PMID:9205951.
