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LKT/APHIDICOLIN/A6229/1 mg

价格
¥3300.00
货号:A6229-1mg
浏览量:38
品牌:LKT Labs
服务
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商品描述
  • Description
  • ProductInfo
  • ShippingandStorage
  • Downloads
  • References

Description

AphidicolinisaditerpeneantibioticinitiallyproducedbyCephalosporumthatexhibitsantiviralactivities.AphidicolininhibitseukaryoticDNAreplicationbyinhibitingDNApolymeraseandinducingSphasecellcyclearrest.Inresearchmodels,aphidicolinisusedtostudycellcyclephases.ThiscompoundalsoinhibitsthegrowthofvacciniavirusinvivobyinhibitingviralDNApolymerase.

ProductInfo

CasNo.

38966-21-1

Purity

≥98%

Formula

C20H34O4

FormulaWt.

338.48

ChemicalName

(3α,4α,5α,17α)-3,17-Dihydroxy-4-methyl-9,15-cyclo-C,18-dinor-14,15-secoandrostane-4,17-dimethanol

Synonym

ICI-69653;NSC-234714

MeltingPoint

227-232°C

Solubility

SolubleinDMSO,ethanol.

Appearance

WhiteCrystalPowder

ShippingandStorage

StoreTemp

-20°C

ShipTemp

Ambient

Downloads

MSDS

A6229MSDSPDF

InfoSheet

A6229InfoSheetPDF

References

WillisJ,DeStephanisD,PatelY,etal.StudyoftheDNAdamagecheckpointusingXenopuseggextracts.JVisExp.2012Nov5;(69):e4449.PMID:23149695.

ZhaoYM,LiJY,LanJP,etal.Cellcycledependenttelomereregulationbytelomeraseinhumanbonemarrowmesenchymalstemcells.BiochemBiophysResCommun.2008May16;369(4):1114-9.PMID:8339310.

DeFilippesFM.Effectofaphidicolinonvacciniavirus:isolationofanaphidicolin-resistantmutant.JVirol.1984Nov;52(2):474-82.PMID:6436508.

ABOUT LKT LABS LKT Laboratories is a biochemical supply company focused on the synthesis, purification, and isolation of small molecules for research applications. Its range of products exhibit known biological activities that have found uses in a wide array of research fields, especially cancer and neuroscience. These products include protein kinase inhibitors, ion channel modulators, and activators. LKT serves the global research community by supplying the highest purity products for use in cell culture models, animal studies, or as reference materials or analytical standards.