Zyagen/GM-CSF Recombinant Protein/7748/1 Ea

价格
¥2940.00
货号:7748
浏览量:125
品牌:Zyagen
服务
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商品描述

Background

GM-CSF is a hematopoietic growth factor that stimulates the development of neutrophils and macrophages and promotes the proliferation and development of early erythroid megakaryocytic and eosinophilic progenitor cells. It is produced in by endothelial cells, monocytes, fibroblasts and T-lymphocytes. GM-CSF inhibits neutrophil migration and enhances the functional activity of the mature end-cells. The human and murine molecules are species-specific and exhibit no cross-species reactivity. Recombinant murine GM-CSF is a 14.2 kDa globular protein consisting of 124 amino acids residues.

 

Specifications

Additional Names
Granulocyte/Macrophage Colony-Stimulating Factor, CSF-2, MGI-1GM, pluripoietin-alpha
Preparation
The ED50 was determined by the dose - dependent stimulation of the proliferation of murine FDC - P1 cells is ? 0.2 ng/ml, corresponding to a specific activity of ? 5 x 106 units/mg.
Location
MAPTRSPITV TRPWKHVEAI KEALNLLDDM PVTLNEEVEV VSNEFSFKKL TCVQTRLKIF EQGLRGNFTK LKGALNMTAS YYQTYCPPTP ETDCETQVTT YADFIDSLKT FLTDIPFECK KPVQK
Source
E. coli
Reactivity
n/a
Tested Application
n/a
Storage
The lyophilized GM-CSF recombinant protein is stable for at least 2 years from date of receipt at -20ËšC. Reconstituted GM-CSF is stable for at least 3 months when stored in working aliquots with a carrier protein at -20ËšC. As with any protein, exposing GM-CSF recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
Species Reactivity
n/a
Purity
Greater than 98% by SDS-PAGE gel and HPLC analyses.

Endotoxin level is less than 0.1 ng per μg (1EU/μg).

 

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