Zyagen/ATG14 Polyclonal Antibody/9780/1 Ea

价格
¥6700.00
货号:9780
浏览量:127
品牌:Zyagen
服务
全国联保
正品保证
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商品描述

ATG14Antibody:Autophagy,theprocessofbulkdegradationofcellularproteinsthroughanautophagosomic-lysosomalpathwayisimportantfornormalgrowthcontrolandmaybedefectiveintumorcells.Itisinvolvedinthepreservationofcellularnutrientsunderstarvationconditionsaswellasthenormalturnoverofcytosoliccomponents.ThisprocessisnegativelyregulatedbyTOR(Targetofrapamycin)throughphosphorylationofautophagyproteinATG1.ATG14isasubunitofaclassIIIphosphatidylinositol(PtdIns)3-kinasecomplexthattargetsthecomplextotheendoplasmicreticulum,thesiteofautophagosomeformation.

Description
ATG14 Antibody
WesternblotanalysisofATG14inhumansmallintestinetissuelysatewithATG14antibodyat(A)1and(B)2μg/mL

Specifications

AdditionalNames
ATG14Antibody:Autophagy-related14,ATG14L,beclin1-associatedautophagy-relatedkeyregulator,beclin1-interactingprotein,BARKOR
Storage
ATG14antibodycanbestoredat4?Cforthreemonthsand-20?C,stableforuptooneyear.Aswithallantibodiescareshouldbetakentoavoidrepeatedfreezethawcycles.Antibodiesshouldnotbeexposedtoprolongedhightemperatures.
Reference
  1. GozuacikDandKimchiA.Autophagyasacelldeathandtumorsuppressormechanism.Oncogene2004;23:2891-906.
  2. KisenGO,TessitoreL,CostelliP,etal.Reducedautophagicactivityinprimaryrathepatocellularcarcinomaandasciteshepatomacells.Carcinogenesis1993;14:2501-5.
  3. KamadaY,FunakoshiT,ShintaniT,etal.Tor-mediatedinductionofautophagyviaApg1proteinkinasecomplex.J.Cell.Biol.2000;150:1507-13.
  4. ItakuraE,KishiC,InoueK,etal.Beclin1formstwodistinctphosphatidylinositol3-kinasecomplexeswithmammalianAtg14andUVRAG.Mol.Biol.Cell2008;19:5360-72.]
PositiveControl
  • Cat.No.1308-HumanSmallIntestineTissueLysate]
Formulation
PhysicalState:Liquid 

Concentration:1mg/mL
ProteinGINumber
50540545
ProteinAccessionNumber
NP_055739
MolecularWeight
54kDa
Disclaimer
Thisproductisforresearchuseonly.
TestedApplication
E,WB,IF
BlockingPeptide
Cat.No.ZP-7043-ATG14Peptide
UserNote
Optimaldilutionsforeachapplicationtobedeterminedbytheresearcher.
Conjugate
None
Purification
ATG14Antibodyisaffinitychromatographypurifiedviapeptidecolumn.
Clonality/Clone
ThisisapolyclonalATG14Antibody.
Isotype
IgG
Host
ATG14antibodywasraisedinrabbit.

Pleaseuseanti-rabbitsecondaryantibodies.
Specificity
AtleastthreeisoformsofATG14areknowntoexist;thisantibodywilldetectallthreeisoforms
Immunogen
ATG14antibodywasraisedagainstan18aminoacidsyntheticpeptidenearthecenterofhumanATG14.
Application
ATG14antibodycanbeusedfordetectionofATG14byWesternblotat1-2μg/mL.Forimmunofluorescencestartat20μg/mL.
Buffer
ATG14AntibodyissuppliedinPBScontaining0.02%sodiumazide.
SpeciesReactivity
H,M,R
Zyagen七五折促销 点击浏览大图收藏此产品 公司名称: 更新时间: 所 在 地: 生产地址: 浏览次数: 上海起发实验试剂有限公司 2017-01-15 02:09:07 上海市 792 【简单介绍】 Zyagen,Zyagen代理,Zyagen上海代理,Zyagen北京代理,Zyagen上海代理,Zyagen国内代理,Zyagen总代理,Zyagen一级代理 【详细说明】 Zyagen,Zyagen代理,Zyagen上海代理,Zyagen北京代理,Zyagen上海代理,Zyagen国内代理,Zyagen总代理,Zyagen一级代理 上海起发实验试剂有限公司American masterTech专业代理,具体产品信息欢迎电询:4006551678 美国Zyagen Laboratories公司位于加利福尼亚州的生物硅谷圣地亚哥,是一家著名的提供基因表达产品和服务的生物公司。从2000年到现在,在基因表达方面的研究及产品的推广一直处于全球地位。Zyagen Laboratories公司由一批训练有素的高水平的学者与研究人员,同时与发展中国家的科学家在生物制药,生物技术等方面有着广泛的合作。