Zyagen/APRIL Rabbit Polyclonal Antibody/5011/1 Ea

价格
¥6300.00
货号:5011
浏览量:61
品牌:Zyagen
服务
全国联保
正品保证
正规发票
签订合同
商品描述

CYT-2415

Background

APRILAntibody:MembersintheTNFsuperfamilyregulateimmuneresponsesandinduceapoptosis.AnovelmemberintheTNFfamilywasrecentlyidentifiedbyseveralgroupsanddesignatedAPRIL(foraproliferation-inducingligand),TALL-2(forTNF-andApoL-relatedLeukocyte-expressedLigand2),andTRDL-1α(forTNFrelateddeathligand1α)inhumanandmouse.TworeceptorsforAPRILwererecentlyidentifiedanddesignatedTACIandBCMA.APRILstimulatesBandTcellproliferation,triggershumoralimmuneresponses,activatesNF-κB,andinducescelldeath.APRILanditscloserelativeofBlySandtheirreceptorsBCMAandTACIareinvolvedindiseasesofautoimmunityandcancer.

 

Description
APRIL Antibody
WesternblotanalysisofAPRILexpressioninJurkatcellswithAPRILantibodyat1μg/mL(A),2μg/mL(B),and4μg/mL(C).
APRIL Antibody
ImmunohistochemistryofAPRILinhumanprostatetissuewithAPRILantibodyat10μg/mL.

 

 

 

 

 

 

 

 

 

 

 

Specifications

AdditionalNames
APRIL(ED2)
AdditionalNames
APRILAntibody:
UserNote
Optimaldilutionsforeachapplicationtobedeterminedbytheresearcher.
Isotype
IgG
MolecularWeight
27kDa
Disclaimer
Thisproductisforresearchuseonly.
Formulation
PhysicalState:Liquid 

Concentration:1mg/mL
Conjugate
None
Clonality/Clone
ThisisapolyclonalAPRILAntibody.
Purification
APRILAntibodyisaffinitychromatographypurifiedviapeptidecolumn.
Host
APRILantibodywasraisedinrabbit.

Pleaseuseanti-rabbitsecondaryantibodies.
Immunogen
APRILantibodywasraisedagainstasyntheticpeptidecorrespondingtoaminoacidswithinaextracellulardomainofhumanAPRIL.
Application
APRILantibodycanbeusedfordetectionofAPRILbyWesternblotat1-4μg/mL.A27kDabandwasdetected.Antibodycanalsobeusedforimmunohistochemistrystartingat10μg/mL.
TestedApplication
E,WB,IHC
Buffer
APRILAntibodyissuppliedinPBScontaining0.02%sodiumazide.
BlockingPeptide
Cat.No.ZP-2415-APRIL(ED2)Peptide
Storage
APRILantibodycanbestoredat4ËšCforthreemonthsand-20ËšC,stableforuptooneyear.Aswithallantibodiescareshouldbetakentoavoidrepeatedfreezethawcycles.Antibodiesshouldnotbeexposedtoprolongedhightemperatures.
SpeciesReactivity
H,M
ProteinGINumber
4507599
ProteinAccessionNumber
NP_003799
Reference

  • HahneM,KataokaT,SchroterM,etal.APRIL,anewligandofthetumornecrosisfactorfamily,stimulatestumorcellgrowth.JExpMed.1998;188(6):1185-90.
  • ShuHB,HuWH,JohnsonH.TALL-1isanovelmemberoftheTNFfamilythatisdown-regulatedbymitogens.JLeukocBiol.1999;65(5):680-3.
  • KellyK,ManosE,JensenG,etal.APRIL/TRDL-1,atumornecrosisfactor-likeligand,stimulatescelldeath.CancerRes.2000;60(4):1021-7.
  • YuG,BooneT,DelaneyJ,etal.APRILandTALL-IandreceptorsBCMAandTACI:systemforregulatinghumoralimmunity.NatImmunol.2000;1(3):252-6.]

CYT-2415

Zyagen七五折促销 点击浏览大图收藏此产品 公司名称: 更新时间: 所 在 地: 生产地址: 浏览次数: 上海起发实验试剂有限公司 2017-01-15 02:09:07 上海市 792 【简单介绍】 Zyagen,Zyagen代理,Zyagen上海代理,Zyagen北京代理,Zyagen上海代理,Zyagen国内代理,Zyagen总代理,Zyagen一级代理 【详细说明】 Zyagen,Zyagen代理,Zyagen上海代理,Zyagen北京代理,Zyagen上海代理,Zyagen国内代理,Zyagen总代理,Zyagen一级代理 上海起发实验试剂有限公司American masterTech专业代理,具体产品信息欢迎电询:4006551678 美国Zyagen Laboratories公司位于加利福尼亚州的生物硅谷圣地亚哥,是一家著名的提供基因表达产品和服务的生物公司。从2000年到现在,在基因表达方面的研究及产品的推广一直处于全球地位。Zyagen Laboratories公司由一批训练有素的高水平的学者与研究人员,同时与发展中国家的科学家在生物制药,生物技术等方面有着广泛的合作。