Characteristics:

cloneDB-1

Referenceslist:

• Flowcytometricanalysisofintracellularinterferon-gammasynthesisinratCD4Tcells.Bernard,I,etal.Eur.CytokineNetw.1998Dec;9:613-8
• Polarizedtype1cytokineresponseandcell-mediatedimmunitydeterminegeneticresistancetomousepox.Chaudhri,Geeta,etal.Proc.Natl.Acad.Sci.U.S.A.2004Jun15;101:9057-62
• InhibitionofT-cellresponsivenessduringexperimentalinfectionswithTrypanosomabrucei:activeinvolvementofendogenousgammainterferon.Darji,A,etal.Infect.Immun.1993Jul;61:3098-102
• Suppressionofratcytomegalovirusreplicationbyantibodiesagainstgammainterferon.Haagmans,BL,etal.J.Virol.1994Apr;68:2305-12
• Effectoftopiramateonthekainate-inducedstatusepilepticus,lipidperoxidationandimmunoreactivityofrats.Kubera,M,etal.PolJPharmacol2004Sep-Oct;56:553-61
• Interferon-gamma-likeimmunoreactivityincertainneuronsofthecentralandperipheralnervoussystem.Ljungdahl,A,etal.J.Neurosci.Res.1989Nov;24:451-6
• Interferon-gamma-likeimmunoreactivityandT-cellMarkerexpressioninratskeletalmusclefibres.Nennesmo,I,etal.BrainRes.1989Dec18;504:306-10
• Interleukin-12p70prolongsallograftsurvivalbyinductionofinterferongammaandnitricoxideproduction.Verma,NirupamaD,etal.Transplantation2006Nov27;82:1324-33
• P0glycoproteinpeptides56-71and180-199dose-dependentlyinduceacuteandchronicexperimentalautoimmuneneuritisinLewisratsassociatedwithepitopespreADIng.Zhu,J,etal.J.Neuroimmunol.2001Mar1;114:99-106
• Isolationandcharacterizationofmonoclonalantibodiesdirectedtoratinterferon-gamma.vanderMeide,PH,etal.LymphokineRes.1989Winter;8:439-49

U-CyTech为干扰素提供基于CPE的抗病毒测定（AVA）测试，也称为细胞病变效应（CPE）抑制测定。在该体外生物测定中，将一个单位定义为将病毒感染的CPE降低50％的干扰素的量。将测试样品的抗病毒生物活性与国际或实验室标准制剂进行比较，并以国际单位（IU）或实验室单位（LU）/ ml表示。 人，大鼠和小鼠干扰素的生物活性分别通过人肺上皮细胞（HEp-2），大鼠胚胎细胞（RATEC）和小鼠成纤维细胞（L929）受到水泡性口腔炎病毒（VSV）攻击来测量。