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苏州工业园区生物纳米园A4#216
联系电话
4000-520-616 / 18915418616
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0512-67156496
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info@ebiomall.com
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https://www.ebiomall.com
商品描述
AML-ETOAntibodyProperties Description Anti-AML-ETO/RUNX1(RABBIT)Antibody-600-401-X43 Host Rabbit TargetSpecies Human KnownCrossReactivity Mouse,Human Clonality PolyclonalIgG Application ELISA:1:100 WesternBlot:1:1,000 PhysicalState Liquid(sterilefiltered) ShippingCondition DryIce Format IgG Label Unconjugated Concentration 0.2mg/mlbyUVabsorbanceat280nm Buffer 0.01MSodiumPhosphate,0.25MSodiumChloride,pH7.2 Preservative 0.05%(w/v)SodiumAzideand0.05%ProClin300 StABIlizer None GeneName RUNX1T1 RelevantLinks UniProtKB-Q06455 GeneID-862 NCBI-NP_001185554.1 |
AML-ETOAntibodyDescription
Background
RUNX1T1isaputativetranscriptionfactorwhichformsaheterodimerwithCBFA2T3.DefectsinRUNX1T1havebeenassociatedwithacutemyeloidleukemia(AML-M2)andmaybeacauseofcolorectalcancer.Anti-AML-ETOAntibodyisidealforresearchinGeneExpressionandCancer.
Synonyms
ProteinCBFA2T1,Cyclin-D-relatedprotein,Eighttwentyoneprotein,ProteinETO,ProteinMTG8,ZincfingerMYNDdomain-containingprotein2,AML1T1,CBFA2T1,CDR,ETO,MTG8,ZMTND2
Immunogen
Anti-AML-ETOAntibodywasproducedinrabbitsbyrepeatedimmunizationswiththreedifferentsyntheticpeptidesfromthehumanAML-ETOfusionprotein.TheantibodyrecognizestheETO(RUNX1T1)partofthefusionprotein.
ImmunogenType
Peptide
StorageCondition
Storevialat-20°Cpriortoopening.Aliquotcontentsandfreezeat-20°Corbelowforextendedstorage.Avoidcyclesoffreezingandthawing.Centrifugeproductifnotcompletelyclearafterstandingatroomtemperature.Thisproductisstableforseveralweeksat4°Casanundilutedliquid.Diluteonlypriortoimmediateuse.
ApplicationNote
Anti-AML-ETOAntibodyissuitableforELISAandWesternBlots.Expectabandapproximately82kDaintheappropriatecelllysateorextract. AsplicevariantofAML-ETOmayalsobedetectedatapproximately70kDa(missing106C-terminalaminoacids).Specificconditionsforreactivityshouldbeoptimizedbytheenduser.
Purity/Specifity
Anti-AML-ETOAntibodywaspurifiedbyaffinitypurification.Crossreactivitywithotherspecieswasnottested.
DisclaimerNote-General
Thisproductisforresearchuseonlyandisnotintendedfortherapeuticordiagnosticapplications.Pleasecontactatechnicalservicerepresentativeformoreinformation.AllproductsofanimaloriginmanufacturedbyRocklandImmunochemicalsarederivedfromstartingmaterialsofNorthAmericanorigin.CollectionwasperformedinUnitedStatesDepartmentofAgriculture(USDA)inspectedfacilitiesandallmaterialshavebeeninspectedandcertifiedtobefreeofdiseaseandsuitableforexportation.Allpropertieslistedaretypicalcharacteristicsandarenotspecifications.Allsuggestionsanddataareofferedingoodfaithbutwithoutguaranteeasconditionsandmethodsofuseofourproductsarebeyondourcontrol.Allclaimsmustbemadewithin30daysfollowingthedateofdelivery.TheProspectiveusermustdeterminethesuitabilityofourmaterialsbeforeadoptingthemonacommercialscale.SuggestedusesofourproductsarenotrecommendationstouseourproductsinviolationofanypatentorasalicenseunderanypatentofRocklandImmunochemicals,Inc.Ifyourequireacommerciallicensetousethismaterialanddonothaveone,thenreturnthismaterial,unopenedto:RocklandInc.,P.O.BOX5199,Limerick,Pennsylvania,USA.
