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蚂蚁淘在线 / 品牌中心 / Rockland / Rockland/Alpha-1-Trypsin Antibody Peroxidase Conjugated/200-103-147-0100/100 µg
商品描述
Alpha-1-TrypsinAntibodyPeroxidaseConjugatedProperties Description Anti-ALPHA-1-ANTI-TRYPSIN(HumanPlasma)(GOAT)AntibodyPeroxidaseConjugated-200-103-147-0100 Host Goat TargetSpecies Human KnownCrossReactivity human Clonality Polyclonal Application ELISA:1:1,000-1:5,000 WesternBlot:1:500-1:2,500 Immunohistochemistry:1:200-1:1,000 OtherDilution:UserOptimized PhysicalState Lyophilized ShippingCondition Ambient Format IgG Label Peroxidase(HorserADIsh) Concentration 1.0mg/mLbyUVabsorbanceat280nm Buffer 0.02MPotassiumPhosphate,0.15MSodiumChloride,pH7.2 ReconstitutionVolume 100µL ReconstitutionBuffer Restorewithdeionizedwater(orequivalent) Preservative 0.01%(w/v)GentamicinSulfate.DoNOTaddSodiumAzide! StABIlizer 10mg/mLBovineSerumAlbumin(BSA)-ImmunoglobulinandProteasefree GeneName SERPINA1 RelevantLinks UniProtKB-P01009 NCBI-P01009.3 GeneID-5265 |
Alpha-1-TrypsinAntibodyPeroxidaseConjugatedDescription
Background
Anti-alpha1Anti-TrypsinAntibodydetectsa1-Anti-Trypsinprotein.a1-Anti-Trypsinisanihibitorofserineproteases.Itsprimarytargetiselastase,butitalsohasamoderateaffinityforplasminandthrombin.Anti-TrypsinirreversIBLyinhibitstrypsin,chymotrypsinandplasminogenactivator.TheaberrantformofAntitrypsininhibitsinsulin-inducedNOsynthesisinplatelets,decreasescoagulationtimeandhasproteolyticactivityagainstinsulinandplasmin.DefectsinSERPINA1arethecauseemphysema,livercirrhosisandliverfailure.Environmentalfactors,particularlycigarettesmoking,greatlyincreasetheriskofemphysemaatanearlierage.Anti-alpha1Anti-TrypsinAntibodyisidealforinvestigatorsinvolvedinCellSignaling,SignalTransductionandCancerresearch.
Synonyms
goatanti-Alpha-1-TrypsinAntibodyHRPConjugation,PeroxidaseConjugatedgoatanti-Alpha-1-TrypsinAntibody,A1ATantibody,AATantibody,Alpha1antiproteinaseantibody,Alpha1antitrypsinantibody,Alpha1proteaseinhibitorantibody
Immunogen
Anti-alpha1Anti-TrypsinAntibodywasproducedbyrepeatedimmunizationswithnativea1-Anti-Trypsinproteinfromhumanplasma.
ImmunogenType
NativeProtein
StorageCondition
Storevialat4°Cpriortorestoration.Forextendedstoragealiquotcontentsandfreezeat-20°Corbelow.Avoidcyclesoffreezingandthawing.Centrifugeproductifnotcompletelyclearafterstandingatroomtemperature.Thisproductisstableforseveralweeksat4°Casanundilutedliquid.Diluteonlypriortoimmediateuse.
ApplicationNote
Anti-a-1-anti-TrypsinAntibodyissuitableforwesternblottingtodetectasinglebandoftheexpectedapparentmolecularweight(~47kDa)andforELISA.Researchersshoulddetermineoptimaltitersforapplicationsthatarenotstatedbelow.
Purity/Specifity
Anti-alpha-1-Anti-TrypsinAntibodyisanIgGfractionantibodypurifiedfrommonospecificantiserumbyamulti-stepprocesswhichincludesdelipidation,saltfractionationandionexchangechromatographyfollowedbyextensivedialysisagainstthebufferstatedabove. Assaybyimmunoelectrophoresisresultedinasingleprecipitinarcagainstanti-Peroxidase,anti-GoatSerumaswellaspurifiedandpartiallypurifieda1-Anti-Trypsin[HumanPlasma]. Crossreactivityagainsta1-Anti-Trypsinfromothersourcesisunknown.
DisclaimerNote-General
Thisproductisforresearchuseonlyandisnotintendedfortherapeuticordiagnosticapplications.Pleasecontactatechnicalservicerepresentativeformoreinformation.AllproductsofanimaloriginmanufacturedbyRocklandImmunochemicalsarederivedfromstartingmaterialsofNorthAmericanorigin.CollectionwasperformedinUnitedStatesDepartmentofAgriculture(USDA)inspectedfacilitiesandallmaterialshavebeeninspectedandcertifiedtobefreeofdiseaseandsuitableforexportation.Allpropertieslistedaretypicalcharacteristicsandarenotspecifications.Allsuggestionsanddataareofferedingoodfaithbutwithoutguaranteeasconditionsandmethodsofuseofourproductsarebeyondourcontrol.Allclaimsmustbemadewithin30daysfollowingthedateofdelivery.TheProspectiveusermustdeterminethesuitabilityofourmaterialsbeforeadoptingthemonacommercialscale.SuggestedusesofourproductsarenotrecommendationstouseourproductsinviolationofanypatentorasalicenseunderanypatentofRocklandImmunochemicals,Inc.Ifyourequireacommerciallicensetousethismaterialanddonothaveone,thenreturnthismaterial,unopenedto:RocklandInc.,P.O.BOX5199,Limerick,Pennsylvania,USA.
