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苏州工业园区生物纳米园A4#216
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4000-520-616 / 18915418616
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0512-67156496
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info@ebiomall.com
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商品描述
AlphaSynucleinAntibodyProperties Description Anti-alphaSynuclein(Mouse)Antibody-500-301-E56 Host Mouse TargetSpecies Human KnownCrossReactivity human,mouse,rat Clonality Monoclonal3H9IgG Application PhysicalState Liquid ShippingCondition DryIce Format ASCITES Label Unconjugated Preservative 0.01%(w/v)SodiumAzide GeneName SNCA RelevantLinks UniProtKB-P37840 GeneID-6622 UniProtKB-P37840.1 |
AlphaSynucleinAntibodyDescription
Background
AlphaSynucleinAntibodydetectsAlphaSynucleinprotein.Alpha-synucleinisapresynapticneuronalproteinthatisthoughttobeinvolvedintheformationofSNAREcomplexes.Mostsignificantly,aggregatedalpha-synucleinisoneofthemajorcomponentsfoundintheLewybodiesthatoccurinParkinson’sdisease(PD)andotherneurodegenerativedisorders.EarlyonsetParkinson"sdiseasemaybecausedbyaduplicationortriplicationofoneofthealphasynucleingenes.Alpha-synucleinisalsofoundintheLewybodiesofpatientswithdiffuseLewybodydiseaseandinclusionsinglialcellsinthebrainsofpatientswithmultiplesystematrophy(MSA)andamyotrophiclateralsclerosis(ALS).Anti-Alpha-synucleinantibodyisidealforinvestigatorsinvolvedinCellSignaling,Neuroscience,SignalTransductionresearch.
Synonyms
mouseanti-AlphaSynucleinAntibody,Non-AbetacomponentofADamyloid,Non-A4componentofamyloidprecursor,NACP
Immunogen
Anti-AlphaSynucleinAntibodywasproducedbyrepeatedimmunizationswithfulllengthhumanalphasynuclein.
ImmunogenType
RecombinantProtein
StorageCondition
Storevialat-20°Cpriortoopening. Thisproductisstableat4°Casanundilutedliquid. Forextendedstorage,aliquotcontentsandfreezeat-20°Corbelow. Avoidcyclesoffreezingandthawing.Diluteonlypriortoimmediateuse.
ApplicationNote
AlphaSynucleinantibodyissuitableforuseinELISA,WesternBlottingandIF.Specificconditionsshouldbeoptimizedbytheenduser.Expectabandofapproximately15kDainsizecorrespondingtothealphasynucleinproteinsintheappropriatecelllysateorextract.
Purity/Specifity
Anti-AlphaSynucleinAntibodyisdirectedagainsthumandAlphaSynucleinprotein.Theantibodywasproducedfromclarifiedmouseasceticfluid.Reactivityisexpectedagainstalphasynucleinfrommostmammalianspeciesbasedon100%sequencehomology.CrossreactivitywithAlphaSynucleinfromothersourceshasnotbeendetermined.
DisclaimerNote-General
Thisproductisforresearchuseonlyandisnotintendedfortherapeuticordiagnosticapplications.Pleasecontactatechnicalservicerepresentativeformoreinformation.AllproductsofanimaloriginmanufacturedbyRocklandImmunochemicalsarederivedfromstartingmaterialsofNorthAmericanorigin.CollectionwasperformedinUnitedStatesDepartmentofAgriculture(USDA)inspectedfacilitiesandallmaterialshavebeeninspectedandcertifiedtobefreeofdiseaseandsuitableforexportation.Allpropertieslistedaretypicalcharacteristicsandarenotspecifications.Allsuggestionsanddataareofferedingoodfaithbutwithoutguaranteeasconditionsandmethodsofuseofourproductsarebeyondourcontrol.Allclaimsmustbemadewithin30daysfollowingthedateofdelivery.TheProspectiveusermustdeterminethesuitABIlityofourmaterialsbeforeadoptingthemonacommercialscale.SuggestedusesofourproductsarenotrecommendationstouseourproductsinviolationofanypatentorasalicenseunderanypatentofRocklandImmunochemicals,Inc.Ifyourequireacommerciallicensetousethismaterialanddonothaveone,thenreturnthismaterial,unopenedto:RocklandInc.,P.O.BOX5199,Limerick,Pennsylvania,USA.
