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苏州工业园区生物纳米园A4#216
联系电话
4000-520-616 / 18915418616
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0512-67156496
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info@ebiomall.com
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https://www.ebiomall.com
商品描述
AKAP4AntibodyProperties Description Anti-AKAP4(RABBIT)Antibody-600-401-X94 Host Rabbit TargetSpecies Human KnownCrossReactivity Human Clonality Polyclonal Application PhysicalState Liquid(sterilefiltered) ShippingCondition DryIce Format IgG Label Unconjugated Concentration 1mg/mLbyUVabsorbanceat280nm Buffer 0.01MSodiumPhosphate,0.25MSodiumChloride,pH7.2 Preservative 0.02%(w/v)SodiumAzide StABIlizer None GeneName AKAP4 RelevantLinks UniProtKB-Q5JQC9 GeneID-8852 NCBI-NP_003877 |
AKAP4AntibodyDescription
Background
TheA-kinaseanchorproteins(AKAPs)areagroupofstructurallydiverseproteins,whichhavethecommonfunctionofbindingtotheregulatorysubunitofproteinkinaseA(PKA)andconfiningtheholoenzymetodiscretelocationswithinthecell(1).AKAP4,alsoknownashAKAP82,isamajorspermfibroussheathproteinthatlocalizestotheentirelengthoftheflagellumofhumansperm(2).IthasbeensuggestedthatAKAP4playsmultiplerolesinspermmotilityandregulationofsignaltransductionpathways(2).AKAP4hasalsobeenpostulatedtobeapotentialbioMarkerforbreastcancer(3).
Synonyms
A-kinaseanchorprotein4,AKAP-4,AKAP82,hAKAP82,CT99,FSC1,HI,PRKA4
Immunogen
Anti-AKAP4antibodywaspreparedfromwholerabbitserumproducedbyrepeatedimmunizationswitha17aminoacidpeptideneartheN-terminusofhumanAKAP4.
ImmunogenType
Peptide
StorageCondition
Storevialat-20°Cpriortoopening.Aliquotcontentsandfreezeat-20°Corbelowforextendedstorage.Avoidcyclesoffreezingandthawing.Centrifugeproductifnotcompletelyclearafterstandingatroomtemperature.Thisproductisstableforseveralweeksat4°Casanundilutedliquid.Diluteonlypriortoimmediateuse.
ApplicationNote
Anti-AKAP4AntibodyhasbeentestedforuseinELISA,WesternBlotting,ImmunohistochemistryandImmunofluorescence.Specificconditionsforreactivityshouldbeoptimizedbytheenduser.Expectabandatapproximately100kDainWesternBlotsofspecificcelllysatesandtissues.
Purity/Specifity
Anti-AKAP4antibodywasaffinitypurifiedfrommonospecificantiserumbyimmunoaffinitychromatography.AKAP4antibodyishumanspecific.Atleastthreeisoformsareknowntoexist;thisantibodywilldetectthetwolongestisoforms.
DisclaimerNote-General
Thisproductisforresearchuseonlyandisnotintendedfortherapeuticordiagnosticapplications.Pleasecontactatechnicalservicerepresentativeformoreinformation.AllproductsofanimaloriginmanufacturedbyRocklandImmunochemicalsarederivedfromstartingmaterialsofNorthAmericanorigin.CollectionwasperformedinUnitedStatesDepartmentofAgriculture(USDA)inspectedfacilitiesandallmaterialshavebeeninspectedandcertifiedtobefreeofdiseaseandsuitableforexportation.Allpropertieslistedaretypicalcharacteristicsandarenotspecifications.Allsuggestionsanddataareofferedingoodfaithbutwithoutguaranteeasconditionsandmethodsofuseofourproductsarebeyondourcontrol.Allclaimsmustbemadewithin30daysfollowingthedateofdelivery.TheProspectiveusermustdeterminethesuitabilityofourmaterialsbeforeadoptingthemonacommercialscale.SuggestedusesofourproductsarenotrecommendationstouseourproductsinviolationofanypatentorasalicenseunderanypatentofRocklandImmunochemicals,Inc.Ifyourequireacommerciallicensetousethismaterialanddonothaveone,thenreturnthismaterial,unopenedto:RocklandInc.,P.O.BOX5199,Limerick,Pennsylvania,USA.
