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苏州工业园区生物纳米园A4#216
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4000-520-616 / 18915418616
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0512-67156496
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info@ebiomall.com
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商品描述
AIMP1AntibodyPropertiesDescription Anti-AIMP1(RABBIT)Antibody-600-401-X90 Host Rabbit TargetSpecies Human KnownCrossReactivity Human,mouse,rat Clonality Polyclonal Application PhysicalState Liquid(sterilefiltered) ShippingCondition DryIce Format IgG Label Unconjugated Concentration 1mg/mLbyUVabsorbanceat280nm Buffer 0.01MSodiumPhosphate,0.25MSodiumChloride,pH7.2 Preservative 0.02%(w/v)SodiumAzide StABIlizer None GeneName AIMP1 RelevantLinks UniProtKB-Q12904 GeneID-9255 NCBI-NP_001135888 |
AIMP1AntibodyDescription
Background
AIMP1(Endothelialmonocyte-activatingpolypeptideII,EMAP2)isaproinflammatorycytokineformonocytesandgranulocytes(1).Itisspecificallyinducedbyapoptosisandisinvolvedinthecontrolofangiogenesis,inflammation,andwoundhealing(1,2).AIMP1wasidentifiedasoneofthreeauxiliaryfactorsofthemammalianaminoacyltRNAsynthetase(ARS)complex.Itbindsandfacilitatesthecatalyticreactionofarginyl-tRNAsynthetase(2,3).RecentstudiesshowthatCD23playsanessentialroleintheAIMP1-inducedimmuneresponseandmightbeatargetinthetreatmentofinflammatorydiseases(4).
Synonyms
AIMP1Antibody,p43,HLD3,EMAP2,SCYE1,EMAPII,AminoacyltRNAsynthasecomplex-interactingmultifunctionalprotein1,Multisynthasecomplexauxiliarycomponentp43,EMAP-2
Immunogen
Anti-AIMP1antibodywaspreparedfromwholerabbitserumproducedbyrepeatedimmunizationswitha19aminoacidpeptideneartheC-terminusofhumanAIMP1.
ImmunogenType
Peptide
StorageCondition
Storevialat-20°Cpriortoopening.Aliquotcontentsandfreezeat-20°Corbelowforextendedstorage.Avoidcyclesoffreezingandthawing.Centrifugeproductifnotcompletelyclearafterstandingatroomtemperature.Thisproductisstableforseveralweeksat4°Casanundilutedliquid.Diluteonlypriortoimmediateuse.
ApplicationNote
Anti-AIMP1AntibodyhasbeentestedforuseinELISA,WesternBlotting,Immunohistochemistry.Specificconditionsforreactivityshouldbeoptimizedbytheenduser.Expectabandatapproximately35kDainWesternBlotsofspecificcelllysatesandtissues.
Purity/Specifity
Anti-AIMP1antibodywasaffinitypurifiedfrommonospecificantiserumbyimmunoaffinitychromatography.AIMP1antibodyishuman,mouseandratreactive.AtleasttwoisoformsofAIMP1areknowntoexist;thisantibodywillrecognizebothisoforms.AIMP1antibodyispredictedtonotcross-reactwithAIMP2.
DisclaimerNote-General
Thisproductisforresearchuseonlyandisnotintendedfortherapeuticordiagnosticapplications.Pleasecontactatechnicalservicerepresentativeformoreinformation.AllproductsofanimaloriginmanufacturedbyRocklandImmunochemicalsarederivedfromstartingmaterialsofNorthAmericanorigin.CollectionwasperformedinUnitedStatesDepartmentofAgriculture(USDA)inspectedfacilitiesandallmaterialshavebeeninspectedandcertifiedtobefreeofdiseaseandsuitableforexportation.Allpropertieslistedaretypicalcharacteristicsandarenotspecifications.Allsuggestionsanddataareofferedingoodfaithbutwithoutguaranteeasconditionsandmethodsofuseofourproductsarebeyondourcontrol.Allclaimsmustbemadewithin30daysfollowingthedateofdelivery.TheProspectiveusermustdeterminethesuitabilityofourmaterialsbeforeadoptingthemonacommercialscale.SuggestedusesofourproductsarenotrecommendationstouseourproductsinviolationofanypatentorasalicenseunderanypatentofRocklandImmunochemicals,Inc.Ifyourequireacommerciallicensetousethismaterialanddonothaveone,thenreturnthismaterial,unopenedto:RocklandInc.,P.O.BOX5199,Limerick,Pennsylvania,USA.