Rockland/AIMP1 Antibody/600-401-X90/100 µg

价格
¥7180.00
货号:600-401-X90
浏览量:118
品牌:Rockland
服务
全国联保
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商品描述

AIMP1AntibodyProperties

Description
Anti-AIMP1(RABBIT)Antibody-600-401-X90
Host
Rabbit
TargetSpecies
Human
KnownCrossReactivity
Human,mouse,rat
Clonality
Polyclonal
Application
ELISA:1:5000-1:10000
WesternBlot:0.5-1µg/mL
Immunohistochemistry:UserOptimized
PhysicalState
Liquid(sterilefiltered)
ShippingCondition
DryIce
Format
IgG
Label
Unconjugated
Concentration
1mg/mLbyUVabsorbanceat280nm
Buffer
0.01MSodiumPhosphate,0.25MSodiumChloride,pH7.2
Preservative
0.02%(w/v)SodiumAzide
StABIlizer
None
GeneName
AIMP1
RelevantLinks
UniProtKB-Q12904
GeneID-9255
NCBI-NP_001135888

AIMP1AntibodyDescription

Background
AIMP1(Endothelialmonocyte-activatingpolypeptideII,EMAP2)isaproinflammatorycytokineformonocytesandgranulocytes(1).Itisspecificallyinducedbyapoptosisandisinvolvedinthecontrolofangiogenesis,inflammation,andwoundhealing(1,2).AIMP1wasidentifiedasoneofthreeauxiliaryfactorsofthemammalianaminoacyltRNAsynthetase(ARS)complex.Itbindsandfacilitatesthecatalyticreactionofarginyl-tRNAsynthetase(2,3).RecentstudiesshowthatCD23playsanessentialroleintheAIMP1-inducedimmuneresponseandmightbeatargetinthetreatmentofinflammatorydiseases(4).
Synonyms
AIMP1Antibody,p43,HLD3,EMAP2,SCYE1,EMAPII,AminoacyltRNAsynthasecomplex-interactingmultifunctionalprotein1,Multisynthasecomplexauxiliarycomponentp43,EMAP-2
Immunogen
Anti-AIMP1antibodywaspreparedfromwholerabbitserumproducedbyrepeatedimmunizationswitha19aminoacidpeptideneartheC-terminusofhumanAIMP1.
ImmunogenType
Peptide
StorageCondition
Storevialat-20°Cpriortoopening.Aliquotcontentsandfreezeat-20°Corbelowforextendedstorage.Avoidcyclesoffreezingandthawing.Centrifugeproductifnotcompletelyclearafterstandingatroomtemperature.Thisproductisstableforseveralweeksat4°Casanundilutedliquid.Diluteonlypriortoimmediateuse.
ApplicationNote
Anti-AIMP1AntibodyhasbeentestedforuseinELISA,WesternBlotting,Immunohistochemistry.Specificconditionsforreactivityshouldbeoptimizedbytheenduser.Expectabandatapproximately35kDainWesternBlotsofspecificcelllysatesandtissues.
Purity/Specifity
Anti-AIMP1antibodywasaffinitypurifiedfrommonospecificantiserumbyimmunoaffinitychromatography.AIMP1antibodyishuman,mouseandratreactive.AtleasttwoisoformsofAIMP1areknowntoexist;thisantibodywillrecognizebothisoforms.AIMP1antibodyispredictedtonotcross-reactwithAIMP2.
DisclaimerNote-General
Thisproductisforresearchuseonlyandisnotintendedfortherapeuticordiagnosticapplications.Pleasecontactatechnicalservicerepresentativeformoreinformation.AllproductsofanimaloriginmanufacturedbyRocklandImmunochemicalsarederivedfromstartingmaterialsofNorthAmericanorigin.CollectionwasperformedinUnitedStatesDepartmentofAgriculture(USDA)inspectedfacilitiesandallmaterialshavebeeninspectedandcertifiedtobefreeofdiseaseandsuitableforexportation.Allpropertieslistedaretypicalcharacteristicsandarenotspecifications.Allsuggestionsanddataareofferedingoodfaithbutwithoutguaranteeasconditionsandmethodsofuseofourproductsarebeyondourcontrol.Allclaimsmustbemadewithin30daysfollowingthedateofdelivery.TheProspectiveusermustdeterminethesuitabilityofourmaterialsbeforeadoptingthemonacommercialscale.SuggestedusesofourproductsarenotrecommendationstouseourproductsinviolationofanypatentorasalicenseunderanypatentofRocklandImmunochemicals,Inc.Ifyourequireacommerciallicensetousethismaterialanddonothaveone,thenreturnthismaterial,unopenedto:RocklandInc.,P.O.BOX5199,Limerick,Pennsylvania,USA.
Rockland Immunochemicals,Inc.(Rockland)成立于1962年,是一家全球生物技术公司,致力于为功能基因组学,基因治疗和药物发现市场的基础,应用和临床研究提供领先的工具。Rockland是一家私有公司,在美国宾夕法尼亚州费城附近拥有一家具有抗体和蛋白质生产能力的制造工厂。高度专业化的主要分销商网络为全球市场提供支持。我们的实验室面积超过60,000平方英尺,生产抗体和基于抗体的工具,这些工具用于帮助定义与细胞功能和疾病相关的机制。我们的声誉建立在对细节,客户服务的关注以及对开发世界一流产品线所需的工具和技术的持续投资上。我们了解并赞赏我们的产品如何帮助解决生命科学研究中的重大全球性问题。在产品进入任何研究实验室之前,我们会非常谨慎地进行验证。每个产品的每批产品都在我们自己的工厂中经过严格的质量控制测试和多重分析验证,以确保性能稳定。