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苏州工业园区生物纳米园A4#216
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4000-520-616 / 18915418616
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0512-67156496
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info@ebiomall.com
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https://www.ebiomall.com
商品描述
AIDAntibodyProperties Description Anti-AID(RABBIT)Antibody-600-401-G74 Host Rabbit TargetSpecies Human KnownCrossReactivity Human,Mouse Clonality Polyclonal Application WesternBlot:1-2ug/mL PhysicalState Liquid(sterilefiltered) ShippingCondition DryIce Format IgG Label Unconjugated Concentration 1mg/mLbyUVabsorbanceat280nm Buffer 0.02MPotassiumPhosphate,0.15MSodiumChloride,pH7.2 Preservative 0.01%(w/v)SodiumAzide GeneName AID RelevantLinks NCBI-AAM95402 UniProtKB-Q8NFC5 |
AIDAntibodyDescription
Background
AIDantibodydetectshumanAID.Activation-inducedcytidinedeaminase(AID)wasinitiallydiscoveredasahomologoftheapolipoproteinBRNA-editingcytidinedeaminase1(APOBEC1)thatshowedcytidinedeaminasepropertiesinstimulatedBcelllines.ItisnecessaryforsomatichypermutationandclassswitchrecombinationinBcells,butinappropriateordysregulatedexpressionAIDisoftenfoundintumorsandBcellneoplasms.AlthoughitisstructurallyandfunctionallysimilartotheAPOBECproteins,itappearsunlikelythatAIDdeaminatesdCtodUresiduesinHIVCDNAasdoesAPOBEC3G.Anti-AIDantibodiesareidealforinvestigatorsinvolvedinApolipoproteinandInfectiousDiseaseresearch.
Immunogen
AIDAntibodywasproducedfromwholerabbitserumpreparedbyrepeatedimmunizationswithapeptidecorrespondingtoaminoacidsnearthec-terminusofhumanAID.
ImmunogenType
Peptide
StorageCondition
Storevialat-20°Cpriortoopening.Aliquotcontentsandfreezeat-20°Corbelowforextendedstorage.Avoidcyclesoffreezingandthawing.Centrifugeproductifnotcompletelyclearafterstandingatroomtemperature.Thisproductisstableforseveralweeksat4°Casanundilutedliquid.Diluteonlypriortoimmediateuse.
ApplicationNote
Anti-AIDAntibodyissuitableforuseinE,WB,andICC.Expectabandapproximately~23.9kDaonspecificlysates.Specificconditionsforreactivityshouldbeoptimizedbytheenduser.
Purity/Specifity
Anti-AIDAntibodywasaffinitypurifiedfrommonospecificantiserumbyimmunoaffinitypurification.ABLASTanalysiswasusedtosuggestcross-reactivitywithAIDwithHumanandMousebasedon100%homologywiththeimmunizingsequence.Cross-reactivitywithAIDfromothersourceshasnotbeendetermined.
DisclaimerNote-General
Thisproductisforresearchuseonlyandisnotintendedfortherapeuticordiagnosticapplications.Pleasecontactatechnicalservicerepresentativeformoreinformation.AllproductsofanimaloriginmanufacturedbyRocklandImmunochemicalsarederivedfromstartingmaterialsofNorthAmericanorigin.CollectionwasperformedinUnitedStatesDepartmentofAgriculture(USDA)inspectedfacilitiesandallmaterialshavebeeninspectedandcertifiedtobefreeofdiseaseandsuitableforexportation.Allpropertieslistedaretypicalcharacteristicsandarenotspecifications.Allsuggestionsanddataareofferedingoodfaithbutwithoutguaranteeasconditionsandmethodsofuseofourproductsarebeyondourcontrol.Allclaimsmustbemadewithin30daysfollowingthedateofdelivery.TheProspectiveusermustdeterminethesuitABIlityofourmaterialsbeforeadoptingthemonacommercialscale.SuggestedusesofourproductsarenotrecommendationstouseourproductsinviolationofanypatentorasalicenseunderanypatentofRocklandImmunochemicals,Inc.Ifyourequireacommerciallicensetousethismaterialanddonothaveone,thenreturnthismaterial,unopenedto:RocklandInc.,P.O.BOX5199,Limerick,Pennsylvania,USA.
