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苏州工业园区生物纳米园A4#216
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4000-520-616 / 18915418616
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0512-67156496
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info@ebiomall.com
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https://www.ebiomall.com
商品描述
AGTR2AntibodyPropertiesDescription Anti-AGTR2(RABBIT)Antibody-600-401-X82 Host Rabbit TargetSpecies Human KnownCrossReactivity Human,mouse,rat Clonality Polyclonal Application PhysicalState Liquid(sterilefiltered) ShippingCondition DryIce Format IgG Label Unconjugated Concentration 1mg/mLbyUVabsorbanceat280nm Buffer 0.01MSodiumPhosphate,0.25MSodiumChloride,pH7.2 Preservative 0.02%(w/v)SodiumAzide StABIlizer None GeneName AGTR2 RelevantLinks UniProtKB-P50052 GeneID-186 NCBI-AAS45437 |
AGTR2AntibodyDescription
Background
AngiotensinIIisapotentvasopressorhormoneandaprimaryregulatorofaldosteronesecretionthatactsthroughatleasttwotypesofreceptors,AGTR1andAGTR2.Itisanimportanteffectorcontrollingbloodpressureandvolumeinthecardiovascularsystemandplaysamajorroleinthedevelopmentofthemammaliankidneyandurinarytract.LikeAGTR1,AGTR2isaseventransmembraneGprotein-coupledreceptor(GPCR),butAGTR2doesnotdemonstratemostoftheclassicfeaturesofGPCRsignaling.AGTR2isinvolvedinawiderangeofactivities,includingtheinductionofneuriteoutgrowthandtheinhibitionofcellularproliferation,inadditiontotheknownfunctionofmediationofvasoconstriction.
Synonyms
AGTR2Antibody,AT2,ATGR2,MRX88,Type-2angiotensinIIreceptor,AngiotensinIItype-2receptor,AT2
Immunogen
Anti-AGTR2antibodywaspreparedfromwholerabbitserumproducedbyrepeatedimmunizationswitha16aminoacidsyntheticpeptidefromneartheinternalregionofhumanAGTR2.
ImmunogenType
Peptide
StorageCondition
Storevialat-20°Cpriortoopening.Aliquotcontentsandfreezeat-20°Corbelowforextendedstorage.Avoidcyclesoffreezingandthawing.Centrifugeproductifnotcompletelyclearafterstandingatroomtemperature.Thisproductisstableforseveralweeksat4°Casanundilutedliquid.Diluteonlypriortoimmediateuse.
ApplicationNote
Anti-AGTR2AntibodyhasbeentestedforuseinELISA,WesternBlotting,andImmunohistochemistry.Specificconditionsforreactivityshouldbeoptimizedbytheenduser.Expectabandatapproximately36kDainWesternBlotsofspecificcelllysatesandtissues.
Purity/Specifity
Anti-AGTR2Antibodywasaffinitypurifiedfrommonospecificantiserumbyimmunoaffinitychromatography.CrossreactivitywithAGTR2fromothersourceshasnotbeendetermined.
DisclaimerNote-General
Thisproductisforresearchuseonlyandisnotintendedfortherapeuticordiagnosticapplications.Pleasecontactatechnicalservicerepresentativeformoreinformation.AllproductsofanimaloriginmanufacturedbyRocklandImmunochemicalsarederivedfromstartingmaterialsofNorthAmericanorigin.CollectionwasperformedinUnitedStatesDepartmentofAgriculture(USDA)inspectedfacilitiesandallmaterialshavebeeninspectedandcertifiedtobefreeofdiseaseandsuitableforexportation.Allpropertieslistedaretypicalcharacteristicsandarenotspecifications.Allsuggestionsanddataareofferedingoodfaithbutwithoutguaranteeasconditionsandmethodsofuseofourproductsarebeyondourcontrol.Allclaimsmustbemadewithin30daysfollowingthedateofdelivery.TheProspectiveusermustdeterminethesuitabilityofourmaterialsbeforeadoptingthemonacommercialscale.SuggestedusesofourproductsarenotrecommendationstouseourproductsinviolationofanypatentorasalicenseunderanypatentofRocklandImmunochemicals,Inc.Ifyourequireacommerciallicensetousethismaterialanddonothaveone,thenreturnthismaterial,unopenedto:RocklandInc.,P.O.BOX5199,Limerick,Pennsylvania,USA.