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苏州工业园区生物纳米园A4#216
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4000-520-616 / 18915418616
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0512-67156496
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info@ebiomall.com
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商品描述
AGTR1AntibodyPropertiesDescription Anti-AGTR1(RABBIT)Antibody-600-401-X81 Host Rabbit TargetSpecies Human KnownCrossReactivity Human,mouse,rat Clonality Polyclonal Application PhysicalState Liquid(sterilefiltered) ShippingCondition DryIce Format IgG Label Unconjugated Concentration 1mg/mLbyUVabsorbanceat280nm Buffer 0.01MSodiumPhosphate,0.25MSodiumChloride,pH7.2 Preservative 0.02%(w/v)SodiumAzide StABIlizer None GeneName AGTR1 RelevantLinks UniProtKB-P30556 GeneID-185 NCBI-EAW78909 |
AGTR1AntibodyDescription
Background
AngiotensinIIisapotentvasopressorhormoneandaprimaryregulatorofaldosteronesecretionthatactsthroughatleasttwotypesofreceptors,AGTR1andAGTR2.Itisanimportanteffectorcontrollingbloodpressureandvolumeinthecardiovascularsystemandplaysamajorroleinthedevelopmentofthemammaliankidneyandurinarytract.AGTR1,thetype1receptor,isthoughttomediatethemajorcardiovasculareffectsofangiotensinIIandmayplayaroleinthegenerationofreperfusionarrhythmiasfollowingrestorationofbloodflowtoischemicorinfarctedmyocardium.AGTR1hasrecentlybeenfoundtoregulatethedifferentiationofbonemarrow-derivedmonocytelineageProgenitorsfromhematopoieticstemcells,indicatingthediversityoftherolesofAGTR1.
Synonyms
AGTR1Antibody,AT1,AG2S,AT1B,AT1R,AT1AR,AT1BR,AT2R1,HAT1R,AGTR1B,AGTR1A,AT2R1B,Type-1angiotensinIIreceptor,AT1
Immunogen
Anti-AGTR1antibodywaspreparedfromwholerabbitserumproducedbyrepeatedimmunizationswitha16aminoacidsyntheticpeptidefromneartheinternalregionofhumanAGTR1.
ImmunogenType
Peptide
StorageCondition
Storevialat-20°Cpriortoopening.Aliquotcontentsandfreezeat-20°Corbelowforextendedstorage.Avoidcyclesoffreezingandthawing.Centrifugeproductifnotcompletelyclearafterstandingatroomtemperature.Thisproductisstableforseveralweeksat4°Casanundilutedliquid.Diluteonlypriortoimmediateuse.
ApplicationNote
Anti-AGTR1AntibodyhasbeentestedforuseinELISA,WesternBlotting,ImmunohistochemistryandImmunofluorescence.Specificconditionsforreactivityshouldbeoptimizedbytheenduser.Expectabandatapproximately41kDainWesternBlotsofspecificcelllysatesandtissues.
Purity/Specifity
Anti-AGTR1Antibodywasaffinitypurifiedfrommonospecificantiserumbyimmunoaffinitychromatography.CrossreactivitywithAGTR1fromothersourceshasnotbeendetermined.
DisclaimerNote-General
Thisproductisforresearchuseonlyandisnotintendedfortherapeuticordiagnosticapplications.Pleasecontactatechnicalservicerepresentativeformoreinformation.AllproductsofanimaloriginmanufacturedbyRocklandImmunochemicalsarederivedfromstartingmaterialsofNorthAmericanorigin.CollectionwasperformedinUnitedStatesDepartmentofAgriculture(USDA)inspectedfacilitiesandallmaterialshavebeeninspectedandcertifiedtobefreeofdiseaseandsuitableforexportation.Allpropertieslistedaretypicalcharacteristicsandarenotspecifications.Allsuggestionsanddataareofferedingoodfaithbutwithoutguaranteeasconditionsandmethodsofuseofourproductsarebeyondourcontrol.Allclaimsmustbemadewithin30daysfollowingthedateofdelivery.TheProspectiveusermustdeterminethesuitabilityofourmaterialsbeforeadoptingthemonacommercialscale.SuggestedusesofourproductsarenotrecommendationstouseourproductsinviolationofanypatentorasalicenseunderanypatentofRocklandImmunochemicals,Inc.Ifyourequireacommerciallicensetousethismaterialanddonothaveone,thenreturnthismaterial,unopenedto:RocklandInc.,P.O.BOX5199,Limerick,Pennsylvania,USA.