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苏州工业园区生物纳米园A4#216
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4000-520-616 / 18915418616
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0512-67156496
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商品描述
ADAMTS2AntibodyProperties Description Anti-ADAMTS2(RABBIT)Antibody-600-401-R07 Host Rabbit KnownCrossReactivity Human,mouse,rat Clonality Polyclonal Application WesternBlot:0.5µg/mL Immunohistochemistry:1:100-1:500 PhysicalState Lyophilized ShippingCondition Ambient Format IgG Label Unconjugated Concentration 100µg/vialbydryweight Buffer 0.9mgNaCl,0.2mgNa2HPO4,0.05mgNaN3 ReconstitutionVolume 100µL ReconstitutionBuffer Restorewithdeionizedwater(orequivalent) Preservative 0.05mgThimerosal StABIlizer 5mgBSA GeneName ADAMTS2 RelevantLinks UniProtKB-O95450 GeneID-9509 NCBI-NP_055059.2 |
ADAMTS2AntibodyDescription
Background
ADAMTS2,Adisintegrinandmetalloproteinasewiththrombospondinmotifs2,alsoknownasprocollagenIN-proteinase(PCI-NP),isanenzymethatinhumansisencodedbytheADAMTS2gene.TheADAMTS2genecontains22exons.ThehumanADAMTS2geneismappedtochromosome5q23-q24byanalysisofsomaticcellhybrids.ADAMTS2isresponsIBLeforprocessingseveraltypesofprocollagenproteins.Procollagensaretheprecursorsofcollagens,theproteinsthataddstrengthandsupporttomanybodytissues.Specifically,thisenzymeclipsashortchainofaminoacidsoffoneendoftheprocollagen.Thisclippingstepisnecessaryforcollagenmoleculestofunctionnormallyandassembleintofibrilsoutsidecells.Thisantibodyissuitableforresearchersinterestedinsignaltransduction,extracellularmatrixantibodiesandcancerresearch.
Synonyms
ProcollagenIN-proteinase,
Immunogen
ADAMTS2affinitypurifiedantibodywaspreparedfromwholerabbitserumproducedbyrepeatedimmunizationswithasyntheticpeptidecorrespondingtoasequenceattheC-terminalofhumanADAMTS2.
ImmunogenType
Peptide
StorageCondition
Storevialat4°Cpriortoopening.Aliquotcontentsandfreezeat-20°Corbelowforextendedstorage.Avoidcyclesoffreezingandthawing.Centrifugeproductifnotcompletelyclearafterstandingatroomtemperature.Thisproductisstableforseveralweeksat4°Casanundilutedliquid.Diluteonlypriortoimmediateuse.
ApplicationNote
Anti-ADAMTS2isusefulforImmunohistochemistry-P,-F,andWesternBlotting.Specificconditionsforreactivityshouldbeoptimizedbytheenduser.Expectabandapproximately~134.8kDacorrespondingtotheappropriatecelllysateorextract.
Purity/Specifity
Anti-ADAMTS2antibodyisdirectedagainsthumanADAMTS2protein. Theproductwasaffinitypurifiedfrommonospecificantiserumbyimmunoaffinitypurification. ABLASTanalysiswasusedtosuggestreactivitywiththisproteinfromhuman,mouse,andratbasedonhomologyfortheimmunogensequence. CrossreactivitywithADAMTS2fromothersourceshasnotbeendetermined.
DisclaimerNote-General
Thisproductisforresearchuseonlyandisnotintendedfortherapeuticordiagnosticapplications.Pleasecontactatechnicalservicerepresentativeformoreinformation.AllproductsofanimaloriginmanufacturedbyRocklandImmunochemicalsarederivedfromstartingmaterialsofNorthAmericanorigin.CollectionwasperformedinUnitedStatesDepartmentofAgriculture(USDA)inspectedfacilitiesandallmaterialshavebeeninspectedandcertifiedtobefreeofdiseaseandsuitableforexportation.Allpropertieslistedaretypicalcharacteristicsandarenotspecifications.Allsuggestionsanddataareofferedingoodfaithbutwithoutguaranteeasconditionsandmethodsofuseofourproductsarebeyondourcontrol.Allclaimsmustbemadewithin30daysfollowingthedateofdelivery.TheProspectiveusermustdeterminethesuitabilityofourmaterialsbeforeadoptingthemonacommercialscale.SuggestedusesofourproductsarenotrecommendationstouseourproductsinviolationofanypatentorasalicenseunderanypatentofRocklandImmunochemicals,Inc.Ifyourequireacommerciallicensetousethismaterialanddonothaveone,thenreturnthismaterial,unopenedto:RocklandInc.,P.O.BOX5199,Limerick,Pennsylvania,USA.
