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公司地址
苏州工业园区生物纳米园A4#216
联系电话
4000-520-616 / 18915418616
传真号码
0512-67156496
电子邮箱
info@ebiomall.com
公司网址
https://www.ebiomall.com
商品描述
ABI1AntibodyProperties Description Anti-Abi1(RABBIT)Antibody-600-401-GT5S Host Rabbit TargetSpecies Mouse KnownCrossReactivity Mouse Clonality Polyclonal Application ELISA:5.0ug/ml WesternBlot:1.0ug/ml PhysicalState Liquid(sterilefiltered) ShippingCondition DryIce Format IgG Label Unconjugated Concentration 1.07mg/mLbyUVabsorbanceat280nm Buffer 0.02MPotassiumPhosphate,0.15MSodiumChloride,pH7.2 Preservative 0.01%(w/v)SodiumAzide Stabilizer None GeneName Abi1 Paired No CellViability No RelevantLinks GeneID-11308 NCBI-NP_001070658.1 UniProtKB-Q8CBW3 |
Abi1AntibodyDescription
Background
Anti-Abi1Antibodywasdesigned,produced,andvalidatedaspartoftheJoyCappelYoungInvestigatorAward(JCYIA).Abi1genehasbeensuggestedtohavearoleininhibitingcellgrowthandencodesanadaptorproteinintheAbelson-interactorfamily.Theproteinisinvolvedinsignaltransduction,actinregulationandcytoskeletalremodeling.StudiessuggestthatAbi1isamemberoftheWAVEcomplexandadysfunctionalcomplexmayallowfortheprogressionofprostatecancer.Anti-Abi1isidealforresearchersinterestedinmelanoma,colonandbreastcancerandothercancerantibodyresearch.
Synonyms
rabbitanti-Abi1Antibody,Abi-1,Abi1,AblInteractor1,Eps8SH3Domain-BindingProtein,Abl-BindingProtein,AbelsonInteractor1,E3B1,SpectrinSH3DomainBindingProtein1, Nap1-bindingprotein,SSH3BP1
Immunogen
Thisaffinitypurifiedantibodywaspreparedfromwholerabbitserumproducedbyrepeatedimmunizationswithasyntheticpeptidecorrespondingtonearc-terminalofthemouseAbi-1protein.
ImmunogenType
Peptide
StorageCondition
Storevialat-20°Corbelowpriortoopening.Thisvialcontainsarelativelylowvolumeofreagent(25µL).Tominimizelossofvolumedilute1:10byadding225µLofthebufferstatedabovedirectlytothevial.Recap,mixthoroughlyandbrieflycentrifugetocollectthevolumeatthebottomofthevial.Usethisintermediatedilutionwhencalculatingfinaldilutionsasrecommendedbelow.Storethevialat-20°Corbelowafterdilution.Avoidcyclesoffreezingandthawing.
ApplicationNote
ThisaffinitypurifiedantibodyhasbeentestedforuseinELISAandwesternblot. Specificconditionsforreactivityshouldbeoptimizedbytheenduser.Expectaband~65kDainsizecorrespondingtoAbi1bywesternblottingintheappropriatecelllysateorextract.
Purity/Specifity
Anti-Abi1isdirectedagainstmouseAbi1.Thisproductisanaffinitypurifiedantibodyproducedbyimmunoaffinitychromatographyusingpeptidecoupledtoagarosebeads. ABLASTanalysiswasusedtosuggestcrossreactivitywiththisproteininhumanandratbasedon100%homologyfortheimmunogensequence.Reactivityagainsthomologuesfromothersourcesisnotknown.
DisclaimerNote-General
Thisproductisforresearchuseonlyandisnotintendedfortherapeuticordiagnosticapplications.Pleasecontactatechnicalservicerepresentativeformoreinformation.AllproductsofanimaloriginmanufacturedbyRocklandImmunochemicalsarederivedfromstartingmaterialsofNorthAmericanorigin.CollectionwasperformedinUnitedStatesDepartmentofAgriculture(USDA)inspectedfacilitiesandallmaterialshavebeeninspectedandcertifiedtobefreeofdiseaseandsuitableforexportation.Allpropertieslistedaretypicalcharacteristicsandarenotspecifications.Allsuggestionsanddataareofferedingoodfaithbutwithoutguaranteeasconditionsandmethodsofuseofourproductsarebeyondourcontrol.Allclaimsmustbemadewithin30daysfollowingthedateofdelivery.TheProspectiveusermustdeterminethesuitabilityofourmaterialsbeforeadoptingthemonacommercialscale.SuggestedusesofourproductsarenotrecommendationstouseourproductsinviolationofanypatentorasalicenseunderanypatentofRocklandImmunochemicals,Inc.Ifyourequireacommerciallicensetousethismaterialanddonothaveone,thenreturnthismaterial,unopenedto:RocklandInc.,P.O.BOX5199,Limerick,Pennsylvania,USA.
