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苏州工业园区生物纳米园A4#216
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4000-520-616 / 18915418616
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0512-67156496
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info@ebiomall.com
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https://www.ebiomall.com
商品描述
A20AntibodyProperties Description Anti-A20(MOUSE)MonoclonalAntibody-200-301-H52 Host Mouse TargetSpecies Human KnownCrossReactivity Human Clonality Monoclonal59A426IgG1kappa Application WesternBlot:2-4µg/mL ImmunoPrecipitation:1-2µg/mL PhysicalState Liquid ShippingCondition DryIce Format IgG1 Label Unconjugated Concentration 0.5mg/mLbyUVabsorbanceat280nm Buffer 0.02MPotassiumPhosphate,0.15MSodiumChloride,pH7.2 Preservative 0.05%(w/v)SodiumAzide StABIlizer 0.05%BSA GeneName TNFAIP3 RelevantLinks UniProtKB-P21580 NCBI-NP_001257436.1 GeneID-7128 |
A20AntibodyDescription
Background
Anti-A20antibodydetectshumanA20.A20(TNFAIP3)isanimportantregulatorofproinflammatorysignalingpathways,includingNK-kBsginaling.A20isupregulatedthroughNF-kB(p50/p55)activation,andsubsequentlydownregulatesNF-kBthroughitsdualfunctionasadeubiquitinaseandubiquitinligase.TheA20monoclonalantibodyhasbeeninstrumentalindiscoveringvariousnuancesofNF-kBregulationandkeytodefiningA20BIOLOGy.Anti-A20antibodyisidealforinvestigatorsinvolvedinNFkappaBandSignalingresearch.
Synonyms
OTUD7C,Tumornecrosisfactoralpha-inducedprotein3,TNFalpha-inducedprotein3,OTUdomain-containingprotein7C,A20p50,A20p37
Immunogen
A20AntibodywasproducedinmicebyrepeatedimmunizationswithrecombinanthumanA20proteinatthec-terminus.
ImmunogenType
RecombinantProtein
StorageCondition
Storevialat-20°Cpriortoopening.Aliquotcontentsandfreezeat-20°Corbelowforextendedstorage.Avoidcyclesoffreezingandthawing.Centrifugeproductifnotcompletelyclearafterstandingatroomtemperature.Thisproductisstableforseveralweeksat4°Casanundilutedliquid.Diluteonlypriortoimmediateuse.
ApplicationNote
Anti-A20antibodyissuitableforuseinFlow(I),IF/ICC,IHC(p),IPandWB.Expectabandapproximately90kDaonspecificlysates.Specificconditionsforreactivityshouldbeoptimizedbytheenduser.
Purity/Specifity
Anti-A20AntibodywaspurifiedbyProteinGchromatography.ABLASTanalysiswasusedtosuggestcross-reactivitywithAnti-A20fromHuman,Mouseandratbasedon100%homologywiththeimmunizingsequence.Cross-reactivitywithAnti-A20fromothersourceshasnotbeendetermined.
DisclaimerNote-General
Thisproductisforresearchuseonlyandisnotintendedfortherapeuticordiagnosticapplications.Pleasecontactatechnicalservicerepresentativeformoreinformation.AllproductsofanimaloriginmanufacturedbyRocklandImmunochemicalsarederivedfromstartingmaterialsofNorthAmericanorigin.CollectionwasperformedinUnitedStatesDepartmentofAgriculture(USDA)inspectedfacilitiesandallmaterialshavebeeninspectedandcertifiedtobefreeofdiseaseandsuitableforexportation.Allpropertieslistedaretypicalcharacteristicsandarenotspecifications.Allsuggestionsanddataareofferedingoodfaithbutwithoutguaranteeasconditionsandmethodsofuseofourproductsarebeyondourcontrol.Allclaimsmustbemadewithin30daysfollowingthedateofdelivery.TheProspectiveusermustdeterminethesuitabilityofourmaterialsbeforeadoptingthemonacommercialscale.SuggestedusesofourproductsarenotrecommendationstouseourproductsinviolationofanypatentorasalicenseunderanypatentofRocklandImmunochemicals,Inc.Ifyourequireacommerciallicensetousethismaterialanddonothaveone,thenreturnthismaterial,unopenedto:RocklandInc.,P.O.BOX5199,Limerick,Pennsylvania,USA.
