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苏州工业园区生物纳米园A4#216
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4000-520-616 / 18915418616
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0512-67156496
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info@ebiomall.com
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https://www.ebiomall.com
商品描述
ARTSAntibodyProperties Description Anti-ARTS(RABBIT)Antibody-600-401-Y64 Host Rabbit TargetSpecies Human KnownCrossReactivity Human Clonality Polyclonal Application PhysicalState Liquid(sterilefiltered) ShippingCondition DryIce Format IgG Label Unconjugated Concentration 1mg/mLbyUVabsorbanceat280nm Buffer 0.01MSodiumPhosphate,0.25MSodiumChloride,pH7.2 Preservative 0.02%(w/v)SodiumAzide StABIlizer None GeneName SEPT4 RelevantLinks UniProtKB-O43236 GeneID-5414 NCBI-AAG45673 |
ARTSAntibodyDescription
Background
Apoptosisisrelatedtomanydiseasesanddevelopment.Mitochondrialproteins,suchascytochromec,Apaf-1,andAIFplayimportantroleinapoptosis.Anovelmitochondrialseptin-likeproteinwasidentifiedrecentlyanddesignatedARTSforapoptosisrelatedproteininTGF-betasignalingpathway.ARTSthatisencodedbythehumanseptinH5/PNUTL2/CDCrel2bgeneislocatedtomitochondriaandtranslocatestothenucleuswhenapoptosisoccurs.ARTSisexpressedinmanytissues.ItenhancescelldeathinducedbyTGF-betaand,toalesserextent,byotherapoptoticagents,suchasTNF-aandFasligand.
Synonyms
ARTSAntibody,H5,ARTS,MART,SEP4,CE5B3,PNUTL2,hucep-7,BRADEION,hCDCREL-2,Septin-4,Apoptosis-relatedproteinintheTGF-betasignalingpathway
Immunogen
Anti-ARTSantibodywaspreparedfromwholerabbitserumproducedbyrepeatedimmunizationswithasyntheticpeptidecorrespondingtoaminoacidsneartheN-terminusofhumanARTS.
ImmunogenType
Peptide
StorageCondition
Storevialat-20°Cpriortoopening.Aliquotcontentsandfreezeat-20°Corbelowforextendedstorage.Avoidcyclesoffreezingandthawing.Centrifugeproductifnotcompletelyclearafterstandingatroomtemperature.Thisproductisstableforseveralweeksat4°Casanundilutedliquid.Diluteonlypriortoimmediateuse.
ApplicationNote
Anti-ARTSAntibodyhasbeentestedforuseinELISA,WesternBlotting,ImmunohistochemistryandImmunofluorescence.Specificconditionsforreactivityshouldbeoptimizedbytheenduser.Expectabandatapproximately55kDainWesternBlotsofspecificcelllysatesandtissues.
Purity/Specifity
Anti-ARTSAntibodywasaffinitypurifiedfrommonospecificantiserumbyimmunoaffinitychromatography.CrossreactivitywithARTSfromothersourceshasnotbeendetermined.
DisclaimerNote-General
Thisproductisforresearchuseonlyandisnotintendedfortherapeuticordiagnosticapplications.Pleasecontactatechnicalservicerepresentativeformoreinformation.AllproductsofanimaloriginmanufacturedbyRocklandImmunochemicalsarederivedfromstartingmaterialsofNorthAmericanorigin.CollectionwasperformedinUnitedStatesDepartmentofAgriculture(USDA)inspectedfacilitiesandallmaterialshavebeeninspectedandcertifiedtobefreeofdiseaseandsuitableforexportation.Allpropertieslistedaretypicalcharacteristicsandarenotspecifications.Allsuggestionsanddataareofferedingoodfaithbutwithoutguaranteeasconditionsandmethodsofuseofourproductsarebeyondourcontrol.Allclaimsmustbemadewithin30daysfollowingthedateofdelivery.TheProspectiveusermustdeterminethesuitabilityofourmaterialsbeforeadoptingthemonacommercialscale.SuggestedusesofourproductsarenotrecommendationstouseourproductsinviolationofanypatentorasalicenseunderanypatentofRocklandImmunochemicals,Inc.Ifyourequireacommerciallicensetousethismaterialanddonothaveone,thenreturnthismaterial,unopenedto:RocklandInc.,P.O.BOX5199,Limerick,Pennsylvania,USA.
