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商品描述
Description:Lactoferrin,Bovine,pAb
Lactoferrinisanapproximately80kDaglycoproteinwhichwasfirstisolatedfrommilkandfoundinepitheliaandmostbodyfluidsandsecretions.Lactoferrinissecretedinplasmabyneutrophils.Itsplasmaconcentrationrepresentsapositiverelationtothetotalpoolofneutrophilsandtherateofneutrophilturnover.Ininflammationlactoferrinisreleasedfromsecondarygranulesofneutrophilicleukocytesintotheextracellularmedium.Thereforetheextracellularlactoferrinconcentrationcanbeusedasanindexforneutrophilactivation.
Lactoferrinisabletostronglybindtoironandconsideredtohaveantibacterialproperties.HumanlactoferrinbindstobacterialproductsthroughitshighlypositivelychargedNterminusandkillsvariousbacteriamostprobablybyinducingintracellularchangesinthesebacteriawithoutaffectingthemembranepermeABIlity.Lactoferrinalsoplaysaroleinsignaltransduction,immunomodulationandhasantiadhesive,anticancer,antiviralactivity.
Lactoferrinisabletostronglybindtoironandconsideredtohaveantibacterialproperties.HumanlactoferrinbindstobacterialproductsthroughitshighlypositivelychargedNterminusandkillsvariousbacteriamostprobablybyinducingintracellularchangesinthesebacteriawithoutaffectingthemembranepermeABIlity.Lactoferrinalsoplaysaroleinsignaltransduction,immunomodulationandhasantiadhesive,anticancer,antiviralactivity.
Specifications:
Catalognumber | HP7001 |
---|---|
Producttype | Polyclonalantibodies |
Quantity | 100µg |
Formulation | 1ml(100µg/ml)0.2µmfilteredantibodysolutioninPBS,containing0.02%sodiumazideand0.1%bovineserumalbumin. |
Application | Immunoassays,Immunoprecipitation,Westernblot |
Isotype | RabbitIg |
Species | Bovine |
Storageandstability | Productshouldbestoredat4 °C.Underrecommendedstorageconditions,productisstableforoneyear. |
Precautions | Forresearchuseonly.Notforuseinoronhumansoranimalsorfordiagnostics.Itistheresponsibilityoftheusertocomplywithalllocal/stateandFederalrulesintheuseofthisproduct.HycultBiotechisnotresponsIBLeforanypatentinfringementsthatmightresultwiththeuseoforderivationofthisproduct. |
Disease | Autoimmunity,Infectiousdiseases |