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商品描述
Description:IL-FABP,Mouse,pAb
Thepolyclonalantibodyrecognizesmouseilealfattyacidbindingprotein(IL-FABPorI-LBP)ofbothnaturalandrecombinantorigin.TheIL-FABPproteinisderivedfromthemouseFABP6gene.FABPsaresmallintracellularproteins(~13-14kDa)withahighdegreeoftissuespecificitythatbindlongchainfattyacids.Theyareabundantlypresentinvariouscelltypesandplayanimportantroleintheintracellularutilizationoffattyacids,transportandmetabolism.ThereareatleastninedistincttypesofFABP,eachshowingaspecificpatternoftissueexpression.Duetoitssmallsize,FABPleaksrapidlyoutofischemicallydamagednecroticcellsleADIngtoariseinserumlevels.Ischemicallydamagedtissuesarecharacterizedhistologicallybyabsence(orlowpresence)ofFABPfacilitatingrecognitionofsuchareas.IL-FABPislocalizedintheintestine,ovary,adrenalsandstomach.
Specifications:
Catalognumber | HP8011 |
---|---|
Producttype | Polyclonalantibodies |
Quantity | 100µg |
Formulation | 1ml(100µg/ml)0.2µmfilteredantibodysolutioninPBS,containing0.1%bovineserumalbuminand0.02%sodiumazide. |
Application | Immunoassays,Paraffinsections,Westernblot |
Use | ForimmunohistologyandWesternblotting,dilutionstobeuseddependondetectionsystemapplied.Itisrecommendedthatuserstestthereagentanddeterminetheirownoptimaldilutions.Thetypicalstartingworkingdilutionis1:50. |
Isotype | RabbitIg |
Species | Mouse |
Crossreactivity | Rat-Yes |
Alias | FABP6,gastrotropin,ileallipid-bindingprotein,I-BABP |
References | 1.Veerkamp,Jetal;Cytoplasmicfattyacid-bindingproteins:theirstructureandgenes.ProgLipidRes1995,34:17 2.Veerkamp,Jetal;StucturalandfunctionalstudiesondifferenthumanFABPtypes.MolCellBiochem1999,192:137 |
StorageandstABIlity | Productshouldbestoredat4 °C.Underrecommendedstorageconditions,productisstableforoneyear. |
Precautions | Forresearchuseonly.Notforuseinoronhumansoranimalsorfordiagnostics.Itistheresponsibilityoftheusertocomplywithalllocal/stateandfederalrulesintheuseofthisproduct.HycultBiotechisnotresponsIBLeforanypatentinfringementsthatmightresultwiththeuseorderivationofthisproduct. |
Disease | Gastroenterology |