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商品描述
Description: TNF-RII, Human, mAb MR2-1, biotinylated
The antibody reacts with the extra-cellular part of the TNF-RII. It also reacts with the soluble receptor. TNF-RII is present on most cell types and is considered to play a prominent role in cell stimulation by TNF-alpha. TNF-RII molecule is shown to be responsible for stimulation of activated T-lymphocytes by TNF-alpha. The antibody cross reacts with rhesus and cynomolgus natural TNF-RII.
Specifications:
Catalog number | HM2008 |
---|---|
Product type | Monoclonal antibodies |
Quantity | 50 µg |
Formulation | 0.5 ml (100 µg/ml) 0.2 µm filtered biotinylated antibody solution in PBS, containing 0.02% sodium azide and 0.1% bovine serum albumin. |
Conjugate | Biotin |
Application | Flow cytometry, Frozen sections, Immuno assays, Western blot |
Use | For immunohistology, flow cytometry and Western blotting dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:10. Advised positive controls for frozen sections are human lymphnodes and for flow cytometry PHA activated T cells. |
Isotype | Mouse IgG1 |
Species | Human |
Cross reactivity | Rhesus monkey - Yes |
References | 1. Leeuwenberg, JFM et al; Slow release of soluble TNF-Receptors by monocytes in vitro. J Immunol 1994, 152: 4036 2. Leeuwenberg, JFM et al; Lipopolysaccharide LPS-mediated soluble TNF-Receptor release and TNF-Receptor expression by monocytes; role of CD14, LPS binding protein and bactericidal/permeability-increasing protein. J Immnol 1994, 152: 5070 |
Storage and stability | Product should be stored at 4 °C. Under recommended storage conditions, product is stable for one year. |
Precautions | For research use only. Not for use in or on humans or animals or for diagnostics. It is the responsibility of the user to comply with all local/state and Federal rules in the use of this product. Hycult Biotech is not responsible for any patent infringements that might result with the use of or derivation of this product. |
Disease | Autoimmunity, Gastroenterology |