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蚂蚁淘在线 / 品牌中心 / Hycult Biotech / Hycult Biotech/L-FABP, Human, mAb L2B10, immuno assay antibody/HM2049-IA/0.5 mg
商品描述
Description:L-FABP,Human,mAbL2B10,immunoassayantibody
ThemonoclonalantibodyL2B10recognizeshumanliverfattyacidbindingprotein(L-FABP)ofbothnaturalandrecombinantorigin.TheL-FABPproteinisderivedfromthehumanFABP1gene.FABPsaresmallintracellularproteins(~13-14kDa)withahighdegreeoftissuespecificitythatbindlongchainfattyacids.Theyareabundantlypresentinvariouscelltypesandplayanimportantroleintheintracellularutilizationoffattyacids,transportandmetabolism.ThereareatleastninedistincttypesofFABP,eachshowingaspecificpatternoftissueexpression.Duetoitssmallsize,FABPleaksrapidlyoutofischemicallydamagednecroticcellsleADIngtoariseinserumlevels.Ischemicallydamagedtissuesarecharacterizedhistologicallybyabsence(orlowpresence)ofFABPfacilitatingrecognitionofsuchareas.L-FABPislocalizedintheliver,kidneyandintestinalepithelium.ThemonoclonalantibodyL2B10isusefultodetectischemicareasofhumanliver.FurThermore,theantibodycanbeusedforthepurificationofhumanL-FABP.
Specifications:
Catalognumber | HM2049-IA |
---|---|
Producttype | Monoclonalantibodies |
Quantity | 0.5mg |
Formulation | 0.5mgof0.2μmproteinGpurifiedantibodysolutioninPBS(exactconcentrationisindicatedonthelabel). |
Application | Frozensections,Immunoassays,Paraffinsections,Westernblot |
ApplicationNotes | P:ForantigenretrievalbothTris-HCLandglycinebuffercanbeused. W:Reducedsampletreatment.Thebandsizeis~15kDa. |
Use | Dilutionstobeuseddependondetectionsystemapplied.Itisrecommendedthatuserstestthereagentanddeterminetheirownoptimaldilutions.Thetypicalstartingworkingdilutionis1:50. |
Isotype | MouseIgG2b |
Species | Human |
Crossreactivity | Baboon-Yes,Canine-Yes,Human-Yes,Rat-Yes,Swine-Yes |
Alias | Humanliverfattyacidbindingprotein,FABP1,Liver-typefattyacid-bindingprotein Genename:FABP1,FABPL |
References | 1.Bax,Detal;High-gradedysplasiainBarrett"sesophagusisassociatedwithincreasedexpressionofcalgranulinAandB.ScandJGastroenterology2007,42:902 |
StorageandstABIlity | Productshouldbestoredat4 °C.Underrecommendedstorageconditions,productisstableforoneyear. |
Precautions | Forresearchuseonly.Notforuseinoronhumansoranimalsorfordiagnostics.Itistheresponsibilityoftheusertocomplywithalllocal/stateandfederalrulesintheuseofthisproduct.HycultBiotechisnotresponsIBLeforanypatentinfringementsthatmightresultwiththeuseorderivationofthisproduct. |
Disease | Cardiologyandmetabolism,Nephrology |