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蚂蚁淘在线 / 品牌中心 / Hycult Biotech / Hycult Biotech/TNF-RII, Human, mAb MR2-1, functional study antibody, low endotoxin/HM2007-FS/0.5 mg
商品描述
Description:TNF-RII,Human,mAbMR2-1,functionalstudyantibody,lowendotoxin
TheantibodyMR2-1reactswiththeextra-cellularpartoftheTNF-RII.Italsoreactswiththesolublereceptor.TNF-RIIispresentonmostcelltypesandisconsideredtoplayaprominentroleincellstimulationbyTNF-alpha.TNF-RIImoleculeisshowntoberesponsIBLeforstimulationofactivatedT-lymphocytesbyTNF-alpha.TheantibodycrossreactswithrhesusandcynomolgusnaturalTNF-RII.
Specifications:
Catalognumber | HM2007-FS |
---|---|
Producttype | Monoclonalantibodies |
Quantity | 0.5mg |
Formulation | 0.5mg(100µg/ml)0.2µmfilteredantibodysolutioninPBS(exactconcentrationisindicatedonthelabel) |
Application | Flowcytometry,Frozensections,Functionalstudies,Immunoassays,Immunofluorescence,Immunoprecipitation,Westernblot |
Use | Forimmunohistology,flowcytometryandWesternblottingdilutionstobeuseddependondetectionsystemapplied.Itisrecommendedthatuserstestthereagentanddeterminetheirownoptimaldilutions.Thetypicalstartingworkingdilutionis1:10.AdvisedpositivecontrolsforfrozensectionsarehumanlymphnodesandforflowcytometryPHAactivatedTcells. |
Isotype | MouseIgG1 |
Species | Human |
Crossreactivity | Cynomolgusmonkey-Yes,Rhesusmonkey-Yes |
References | 1.Leeuwenberg,JFMetal;SlowreleaseofsolubleTNF-Receptorsbymonocytesinvitro.JImmunol1994,152:4036 2.Leeuwenberg,JFMetal;LipopolysaccharideLPS-mediatedsolubleTNF-ReceptorreleaseandTNF-Receptorexpressionbymonocytes;roleofCD14,LPSbindingproteinandbactericidal/permeABIlity-increasingprotein.JImmnol1994,152:5070 3.Marchetti,Letal;Tumornecrosisfactor(TNF)-mediatedneuroprotectionagainstglutamate-inducedexcitotoxicityisenhancedbyN-methyl-D-aspartatereceptoractivation.EssentialroleofaTNFreceptor2-mediatedphosphatidylinositol3-kinase-dependentNF-kappaBpathway.JBiolChem2004,279:32869 |
Storageandstability | Productshouldbestoredat4 °C.Underrecommendedstorageconditions,productisstableforoneyear. |
Precautions | Forresearchuseonly.Notforuseinoronhumansoranimalsorfordiagnostics.Itistheresponsibilityoftheusertocomplywithalllocal/stateandFederalrulesintheuseofthisproduct.HycultBiotechisnotresponsibleforanypatentinfringementsthatmightresultwiththeuseoforderivationofthisproduct. |
Disease | Autoimmunity,Gastroenterology |