Doxoves® - PEGylated Liposomal Doxorubicin HCl
Doxorubicin HCl is loaded into PEGylated liposomes composed of HSPC/CHOL/mPEG2000-DSPE (56.2:38.5:5.3 mol/mol) with ammonium gradient by the active loading approach. It is comparable to the commercial product DOXIL®. The liposomes are prepared to very high quality with consistent lot-lot characteristics. Narrow particle size distribution and high drug encapsulation efficiency.Note the high drug concentration (4mg/mL compared to 2 mg/mL for DOXIL®) allows the researchers to perform experiments at higher concentration/doses.
Product For Research only and NOT for Human Use
Specifications
Product code: F30204B-D
Lipid composition: HSPC/CHOL/mPEG2000-DSPE (56.2:38.5:5.3 mol/mol)
Lipid concentration: 40.0 mM
Doxorubicin HCl: 4.0 mg/mL
Encapsulation efficiency: > 95% (typically 98%)
Loading battery: 250 mMammonium sulfate
Mean particle size: 85 nm (80 - 90 nm)
External solution: 10% sucrose, 10 mM histidine, pH 6.5
Shelf-life:6 months, storage:2-8 degree C
HSPC: hydrogenated phosphatidylcholine (Soy)
CHOL: cholesterol
mPEG2000-DSPE: 18:0 PEG2000 PE:1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000]
Clophosome ®（中性氯氟松）和Clophosome ®-A（阴离子氯氟松）是目前市场上最理想的用于体内/体外巨噬细胞耗竭的氯磷酸盐二钠脂质体。该组产品适用于多种给药方式，包括尾静脉注射、腹腔注射、皮下注射、气管给药以及直接注射等。其中Clophosome ®（中性氯氟松）的巨噬细胞耗竭率可达80%以上，而Clophosome ®-A（阴离子氯氟松）的巨噬细胞耗竭率更是高达90%以上。并且在保持常规使用剂量的情况下，Clophosome ®-A（阴离子氯氟松）可实现数周的长期巨噬细胞耗竭，以及体外高效巨噬细胞的耗竭功能。 现货产品 蚂蚁淘现为您提供Clophosome®氯氟松现货，为您解决货期问题，不仅提供阴离子氯氟松，中性氯氟松，还有带control的combo。Control为未包含活性氯磷酸的空白脂质体，在物理性能上与脂质体类似，但不具有耗竭巨噬细胞的功能，为您提供阴性对照，让您的实验更为准确。 货号 产品名称 规格 F70101C-N-2 Clophosome®, Clodronate Liposomes (Neutral) 2ml F70101C-A-2 Clophosome®-A - Clodronate Liposomes (Anionic) 2ml F70101C-AC-2 Combo: Clophosome®-A (Anionic ) and Control Liposomes 2ml F70101C-NC-2 Combo: Clophosome®-N (neutral) and Control Liposomes 2ml 免费试用装 Formumax公司提供免费的Clophosome®可供试用，小伙伴们快来申请试用吧！（*直接联系蚂蚁淘申请试用即可） 结果分享 BioLegend小鼠巨噬细胞常见检测Marker四色搭配方案 除了以上列举的巨噬细胞耗竭剂以外，Formumax还能提供各类高效能Clophosome®产品以及Clophosome®荧光对照脂质体，小伙伴们赶快行动起来吧！
