Clophosome®-A-Clodronateliposomes(Anionic)
Clophosome®-A,negatively-chargedclodronateliposomes,offerssuperiorefficiencyofmacrophagedepletion.ClodronatemoleculesareencapsulatedinLUVliposomesforsuperioractivity,physicalandchemicalstABIlity,andconvenienceofuse.Itisformulatedtoanexceptionallyhighclodronate/lipidratio.FreeclodronateiscleanedoutandtheLiposomalencapsulationefficiencyofclodronateismorethan90%.Clophosomeliposomesremainhomogenousevenafterlongtermstorageinfridge.Itisnotviscousandeasytoinjectevenwithfineneedles.Itismanufacturedsterileforlongtermshelf-life.
Theproductissuitablefordosingwithvariousroutesincludingintravenous,intraperitoneal,subcutaneous,intranasal,intratrachealandetc.Wehaveachieved>90%depletioninsplenicmacrophages(redpulpmacrophages)24hoursafterasingle0.2mLintravenousinjection.Astartingdoseof0.15-2mL(i.v.ori.p.)for20-25ganimalbodyweightisrecommendedforgoodconsistencyinmacrophagedepletion.Optimizationisrecommendedforspecificapplications.
Specifications
Productname:Clophosome®-A
Productcode:F70101C-A
Active:clodronatedisodium.CAS:22560-50-5,7mg/mL
Lipidcomposition:phosphatidylglycerol,phosphatidylcholineandcholesterol
Bulksolution:phosphatebufferedsaline(20mMsodiumphosphate,09wt%NaCl),pH7.0-7.5
Shelf-life:6monthsguaranteedforunopenedvialsat2-8degreeC(guaranteedstartingfromthedateofdelivery,replacementonly)
SeesampleCofA
Clophosome ®(中性氯氟松)和Clophosome ®-A(阴离子氯氟松)是目前市场上最理想的用于体内/体外巨噬细胞耗竭的氯磷酸盐二钠脂质体。该组产品适用于多种给药方式,包括尾静脉注射、腹腔注射、皮下注射、气管给药以及直接注射等。其中Clophosome ®(中性氯氟松)的巨噬细胞耗竭率可达80%以上,而Clophosome ®-A(阴离子氯氟松)的巨噬细胞耗竭率更是高达90%以上。并且在保持常规使用剂量的情况下,Clophosome ®-A(阴离子氯氟松)可实现数周的长期巨噬细胞耗竭,以及体外高效巨噬细胞的耗竭功能。 现货产品 蚂蚁淘现为您提供Clophosome®氯氟松现货,为您解决货期问题,不仅提供阴离子氯氟松,中性氯氟松,还有带control的combo。Control为未包含活性氯磷酸的空白脂质体,在物理性能上与脂质体类似,但不具有耗竭巨噬细胞的功能,为您提供阴性对照,让您的实验更为准确。 货号 产品名称 规格 F70101C-N-2 Clophosome®, Clodronate Liposomes (Neutral) 2ml F70101C-A-2 Clophosome®-A - Clodronate Liposomes (Anionic) 2ml F70101C-AC-2 Combo: Clophosome®-A (Anionic ) and Control Liposomes 2ml F70101C-NC-2 Combo: Clophosome®-N (neutral) and Control Liposomes 2ml 免费试用装 Formumax公司提供免费的Clophosome®可供试用,小伙伴们快来申请试用吧!(*直接联系蚂蚁淘申请试用即可) 结果分享 BioLegend小鼠巨噬细胞常见检测Marker四色搭配方案 除了以上列举的巨噬细胞耗竭剂以外,Formumax还能提供各类高效能Clophosome®产品以及Clophosome®荧光对照脂质体,小伙伴们赶快行动起来吧!