Alendrosome™-Alendronateliposomes(Neutral)
WearelookingforresearcherstotestourAlendrosome™products,pleasecontactusifyouareinterested
Specifications
Active:alendronatesodium(CAS121268-17-5),2.0mg/mL
Volume:10.0mL
Lipidcomposition:phosphatidylcholineandcholesterol
Internal/Externalsolution:phosphatebufferedsaline(20mMsodiumphosphate,09wt%NaCl),pH7.0-7.5
Usage:warmtoroomtemperatureandmixwellbeforeuse.
Dosage:thisisanewproductandnorecommendeddoseisavailableatthispoint.Referthefollowingliteratureforadditionalinformation
References
BenjaminJ.Burwitzetal.TechnicalAdvance:Liposomalalendronatedepletesmonocytesandmacrophagesinthenonhumanprimatemodelofhumandisease.JLeukocBiol.2014Sep;96(3):491–501.PMC4632165(Link)
RenateFrei,Comparisonofcytotoxicpropertiesoffreeandliposomalbisphosphonatesinvitro(DiplomaThesis)(Link)
MönkkönenJ,vanRooijenN,YlitaloP.,EffectsofClodronateandpamidronateonsplenicandhepaticphagocyticcellsofmice.PharmacolToxicol.1991Apr;68(4):284-6.(Link) MakkonenN,HirvonenMR,TeräväinenT,SavolainenK,MönkkönenJ.,DifferenteffectsofthreebisphosphonatesonnitricoxideproductionbyRAW264macrophage-likecellsinvitro.JPharmacolExpTher.1996May;277(2):1097-102(link)
vanRooijenN,KorsN.Effectsofintracellulardiphosphonatesoncellsofthemononuclearphagocytesystem:invivoeffectsofliposome-encapsulateddiphosphonatesondifferentmacrophagesubpopulationsinthespleen.CalcifTissueInt.1989Sep;45(3):153-6.(Link)
EpsteinH.etal.,PreparationofalendronateliposomesforenhancedstABIlityandbioactivity:invitroandinvivocharacterization.AAPSJ.2008Dec;10(4):505-15.Epub2008Oct21.(Link)
Clophosome ®(中性氯氟松)和Clophosome ®-A(阴离子氯氟松)是目前市场上最理想的用于体内/体外巨噬细胞耗竭的氯磷酸盐二钠脂质体。该组产品适用于多种给药方式,包括尾静脉注射、腹腔注射、皮下注射、气管给药以及直接注射等。其中Clophosome ®(中性氯氟松)的巨噬细胞耗竭率可达80%以上,而Clophosome ®-A(阴离子氯氟松)的巨噬细胞耗竭率更是高达90%以上。并且在保持常规使用剂量的情况下,Clophosome ®-A(阴离子氯氟松)可实现数周的长期巨噬细胞耗竭,以及体外高效巨噬细胞的耗竭功能。
现货产品
蚂蚁淘现为您提供Clophosome®氯氟松现货,为您解决货期问题,不仅提供阴离子氯氟松,中性氯氟松,还有带control的combo。Control为未包含活性氯磷酸的空白脂质体,在物理性能上与脂质体类似,但不具有耗竭巨噬细胞的功能,为您提供阴性对照,让您的实验更为准确。
货号
产品名称
规格
F70101C-N-2
Clophosome®, Clodronate Liposomes (Neutral)
2ml
F70101C-A-2
Clophosome®-A - Clodronate Liposomes (Anionic)
2ml
F70101C-AC-2
Combo: Clophosome®-A (Anionic ) and Control Liposomes
2ml
F70101C-NC-2
Combo: Clophosome®-N (neutral) and Control Liposomes
2ml
免费试用装
Formumax公司提供免费的Clophosome®可供试用,小伙伴们快来申请试用吧!(*直接联系蚂蚁淘申请试用即可)
结果分享
BioLegend小鼠巨噬细胞常见检测Marker四色搭配方案
除了以上列举的巨噬细胞耗竭剂以外,Formumax还能提供各类高效能Clophosome®产品以及Clophosome®荧光对照脂质体,小伙伴们赶快行动起来吧!