Clophosome®-A- Clodronate Liposomes (Anionic)
Clophosome®-A, negatively-charged clodronate liposomes, offers superior efficiency of macrophagedepletion. Clodronate molecules are encapsulated in LUV liposomes for superior activity, physical and chemical stability, and convenience of use. It is formulated to an exceptionally high clodronate/lipid ratio. Free clodronate is cleaned out and the liposomal encapsulation efficiency of clodronateis more than 90%.Clophosome liposomes remain homogenous even after long term storage in fridge. It is not viscous and easy to inject even with fine needles.It is manufactured sterilefor long term shelf-life.
The product is suitable for dosing with various routes includingintravenous, intraperitoneal, subcutaneous, intranasal,intratracheal and etc. We have achieved > 90%depletion in splenicmacrophages (red pulp macrophages) 24 hours after a single 0.2 mL intravenous injection.A starting dose of 0.15-2 mL (i.v. or i.p.) for 20-25ganimal body weight is recommended for good consistency in macrophage depletion. Optimization is recommended for specific applications.
Specifications
Product name: Clophosome®-A
Product code: F70101C-A
Active: clodronate disodium.CAS: 22560-50-5, 7 mg/mL
Lipid composition:phosphatidylglycerol,phosphatidylcholine and cholesterol
Bulk solution:phosphate buffered saline (20mMsodiumphosphate, 09wt% NaCl), pH 7.0-7.5
Shelf-life:6 monthsguaranteed for unopened vials at 2-8 degree C (guaranteed starting from the date of delivery, replacement only)
See sample CofA
Clophosome ®（中性氯氟松）和Clophosome ®-A（阴离子氯氟松）是目前市场上最理想的用于体内/体外巨噬细胞耗竭的氯磷酸盐二钠脂质体。该组产品适用于多种给药方式，包括尾静脉注射、腹腔注射、皮下注射、气管给药以及直接注射等。其中Clophosome ®（中性氯氟松）的巨噬细胞耗竭率可达80%以上，而Clophosome ®-A（阴离子氯氟松）的巨噬细胞耗竭率更是高达90%以上。并且在保持常规使用剂量的情况下，Clophosome ®-A（阴离子氯氟松）可实现数周的长期巨噬细胞耗竭，以及体外高效巨噬细胞的耗竭功能。 现货产品 蚂蚁淘现为您提供Clophosome®氯氟松现货，为您解决货期问题，不仅提供阴离子氯氟松，中性氯氟松，还有带control的combo。Control为未包含活性氯磷酸的空白脂质体，在物理性能上与脂质体类似，但不具有耗竭巨噬细胞的功能，为您提供阴性对照，让您的实验更为准确。 货号 产品名称 规格 F70101C-N-2 Clophosome®, Clodronate Liposomes (Neutral) 2ml F70101C-A-2 Clophosome®-A - Clodronate Liposomes (Anionic) 2ml F70101C-AC-2 Combo: Clophosome®-A (Anionic ) and Control Liposomes 2ml F70101C-NC-2 Combo: Clophosome®-N (neutral) and Control Liposomes 2ml 免费试用装 Formumax公司提供免费的Clophosome®可供试用，小伙伴们快来申请试用吧！（*直接联系蚂蚁淘申请试用即可） 结果分享 BioLegend小鼠巨噬细胞常见检测Marker四色搭配方案 除了以上列举的巨噬细胞耗竭剂以外，Formumax还能提供各类高效能Clophosome®产品以及Clophosome®荧光对照脂质体，小伙伴们赶快行动起来吧！
