General Information

Product

Relaxin 1 Antibody

Description

Affinity Purified Relaxin receptor 1 Antibody

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 100-150 on rat relaxin receptor 1 protein.

Accession #

NCBI: NP_958820

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

.5 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Immunoprecipitation

1:150

Western Blot

1:500

Protein

Uniprot #

Q6R6I6

Overview

Receptor for relaxins. The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP. Binding of the ligand may also activate a tyrosine kinase pathway that inhibits the activity of a phosphodiesterase that degrades cAMP.

Molecular Function

G-protein coupled receptor activity, metal ion binding; Adenylate cyclase-activating G-protein coupled receptor signaling pathway

Subcellular Location

Cell membrane; Multi-pass membrane protein

Expression

Detected in brain cortex, and at low levels in testis.

Structure

Belongs to the G-protein coupled receptor 1 family.

Contains 1 LDL-receptor class A domain.

Contains 11 LRR (leucine-rich) repeats.

Alternative Nomenclature

H1 antibody

H1RLX antibody

Preprorelaxin H1 antibody

Prorelaxin antibody

Prorelaxin H1 antibody

Relaxin 1 (H1) antibody

Relaxin A chain antibody

Relaxin1 antibody

RelaxinH1 antibody

RLN1 antibody

RLXH1 antibody