General Information |
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Product |
PDE11A3 Antibody Affinity Purified |
Description | Affinity Purified Phosphodiesterase 11A3 Antibody |
Verified Applications | ELISA, IMM, WB |
Host | Rabbit |
Species Cross Reactivity | Human, Mouse, Rat |
Immunogen | Synthetic peptide unique to PDE11A3 variant |
Accession # | GenBank: AB038041.1 |
Physical Properties | |
Quantity |
100 µg |
Volume | 200 µl |
Concentration | 0.68 µg/µl in antibody stabilization buffer |
Form | Affinity Purified |
Clonality | Polyclonal |
Storage | -20⁰C for long term storage |
Application Protocol |
DB | 1:10,000 |
ELISA | 1:10,000 |
Immunoprecipitation | 1:250 |
Western Blot | 1:500 |
Protein |
Uniprot # |
Q9HCR9 |
Overview | Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides cAMP and cGMP. Catalyzes the hydrolysis of both cAMP and cGMP to 5"-AMP and 5"-GMP, respectively. |
Molecular Function | Hydrolase, metal-ion binding, cGMP binding |
Subcellular Location | Cytoplasm |
Expression | Isoform 1 is present in prostate, pituitary, heart and liver. It is however not present in testis nor in penis, suggesting that weak inhibition by Tadalafil is not relevant (at protein level). Isoform 2 may be expressed in testis. Isoform 4 is expressed |
Alternative Nomenclature | PDE11A antibody PDE11A3 antibody PPNAD2 antibody |
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