General Information

Product

PAX2 isoform a + e Antibody

Description

Affinity Purified Paired box protein Pax-2 isoform a and Pax-2 isoform e Antibody C-epitope

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 205-235 on human PAX2 isoform d protein.

Specificity

This antibody will detect Pax-2 isoform a and Pax-2 isoform e. Will not detect other Pax-2 isoforms.

Accession #

NCBI: NP_003978.2

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.75-0.95 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Clonality

Polyclonal

Determinant

C-epitope

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:10,000

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

Q02962

Overview

Probable transcription factor that may have a role in kidney cell differentiation. Has a critical role in the development of the urogenital tract, the eyes, and the CNS.

Molecular Function

Developmental protein, core promoter proximal region sequence-specific DNA binding, DNA binding

Subcellular Location

Nucleus

Expression

Expressed in primitive cells of the kidney, ureter, eye, ear and central nervous system.

Structure

Mainly in fetal kidney and juvenile nephrogenic rests.

Alternative Nomenclature

Paired box 2 antibody

Paired box gene 2 antibody

paired box protein 2 antibody

Paired box protein Pax 2 antibody

Pax 2 antibody