General Information

Product

LAMP2 Antibody

Description

Affinity Purified Lysosome-associated membrane glycoprotein 2 Antibody

Verified Applications

DB, ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse

Predicted: Rat

Immunogen

Synthetic peptide taken within amino acid region 260-310 on human lysosomal membrane glycoprotein-2.

Accession #

GenBank: AAB41647.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.68-0.70 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:4,000

ELISA

1:4,000

Immunoprecipitation

1:150

Western Blot

1:500

Protein

Uniprot #

P13473

Overview

Implicated in tumor cell metastasis. May function in protection of the lysosomal membrane from autodigestion

Molecular Function

enzyme binding

Subcellular Location

Cell membrane, Endosome, Lysosome, Membrane

Expression

LAMP-2A is highly expressed in placenta, lung and liver, less in kidney and pancreas, low in brain and skeletal muscle.LAMP-2B is highly expressed in skeletal muscle, less in brain, placenta, lung, kidney and pancreas, very low in liver.

Structure

Belongs to the LAMP family

Alternative Nomenclature

CD107 antigen-like family member B antibody

CD107b antibody

LAMP 2 antibody

LAMP 2C antibody

LAMPB antibody

LGP110 antibody

Lysosome associated membrane protein 2 antibody

MAC3 antibody