General Information

Product

Calponin Antibody

Description

Affinity Purified Calponin 1, basic, smooth muscle Antibody N-epitope

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Monkey, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 120-170 on human Calponin 1, basic, smooth muscle protein.

Accession #

NCBI: XP_005259798.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.75 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

N-epitope

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Immunoprecipitation

1:150

Western Blot

1:500

Protein

Uniprot #

B7Z7E1

Overview

Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.

Molecular Function

Actin-Binding; actomyosin structure organization

Subcellular Location

Cytoskeleton; Focal Adhesion

Expression

Smooth muscle, and tissues containing significant amounts of smooth muscle.

Structure

Belongs to the calponin family.UniRule annotation

Contains 1 CH (calponin-homology) domain.

Contains 3 calponin-like repeats.

Alternative Nomenclature

Basic calponin antibody

Calponin 1 antibody

Calponin 1 basic smooth muscle antibody

Calponin H1 antibody

Calponin H1 smooth muscle antibody

Calponins basic antibody

CNN 1 antibody

Sm Calp antibody

SMCC antibody

smooth muscle antibody