Nordicmubio/Rabbit anti Drosophila Sphingomyelin synthase-related protein 1/X1861P

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货号:X1861P
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商品描述
Rabbit anti Drosophila Sphingomyelin synthase-related protein 1Catalogue number: X1861P

IsotypeIgG
Product Type Polyclonal Antibody
Units100 µg
HostRabbit
Species reactivity Drosophila
Application Western Blotting

BackgroundSphingomyelin synthases are enzymes that mediate the biosynthesis of sphingolipid headgroups. Sphingomyelin synthase 1 and 2 (SMS1 and SMS2) mediate the biosynthesis of sphingomyelin, a central sphingolipid in mammalian cells.In addition to SMS1 and SMS2, a third SMS-related protein, SMSr, is known, however its function remains largely unknown.SMSr also occurs in organisms which lack sphingomyelin, such as the fruit fly Drosophila melanogaster.Its function appears to be biosynthesis of ethanolamine phosphorylceramide (EPC), a sphingolipid structurally related to sphingomyelin.SMSr has also been found in mammals as well.

Synonyms: SMSr

Source

Immunogen: Recombinant SMSr derived from Drosophila .

Product

Product Form: Unconjugated

Formulation: Provided as solution in phosphate buffered saline with 0.08% sodium azide

Purification Method: Ammonium Sulfate Precipitation

Concentration: See vial for concentration

ApplicationsOptimal concentration should be evaluated by serial dilutions.

Functional Analysis: Western Blotting

Positive Control: Recombinant sphingomelin synthase protein

StorageProduct should be stored at -20ºC. Aliquot to avoid freeze/thaw cycles

Product Stability: Products are stable for one year from purchase when stored properly

Shipping Conditions: Ship at ambient temperature, freeze upon arrival

CautionThis product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. It may contain hazardous ingredients. Please refer to the Safety Data Sheets (SDS) for additional information and proper handling procedures. Dispose product remainders according to local regulations.This datasheet is as accurate as reasonably achievable, but Nordic-MUbio​ accepts no liability for any inaccuracies or omissions in this information.

References1: Dickson, R. C. (1998) Annu. Rev. Biochem. 67, 27–482: Pewzner-Jung, Y., Ben-Dor, S., and Futerman, A. H. (2006) J. Biol. Chem. 281, 25001–250053: Mandon, E. C., Ehses, I., Rother, J., van Echten, G., and Sandhoff, K. (1992) J. Biol. Chem. 267, 11144–111484: Jeckel, D., Karrenbauer, A., Burger, K. N., van Meer, G., and Wieland, F. (1992) J. Cell Biol. 117, 259–2675: Futerman, A. H., Stieger, B., Hubbard, A. L., and Pagano, R. E. (1990) J. Biol. Chem. 265, 8650–86576: Huitema, K., van den Dikkenberg, J., Brouwers, J. F., and Holthuis, J. C. (2004) EMBO J. 23, 33–447: Yamaoka, S., Miyaji, M., Kitano, T., Umehara, H., and Okazaki, T. (2004) J. Biol. Chem. 279, 18688–186938: Ullman, M. D., and Radin, N. S. (1974) J. Biol. Chem. 249, 1506–15129: Voelker, D. R., and Kennedy, E. P. (1982) Biochemistry 21, 2753–275910: van Helvoort, A., van't Hof, W., Ritsema, T., Sandra, A., and van Meer, G. (1994) J. Biol. Chem. 269, 1763–176911: Muehlenberg, B. A., Sribney, M., and Duffe, M. K. (1972) Can J. Biochem. 50, 166–17312: Hannun, Y. A., and Obeid, L. M. (2002) J. Biol. Chem. 277, 25847–2585013: Wiegmann, K., Schutze, S., Machleidt, T., Witte, D., and Kronke, M. (1994) Cell 78, Spiegel, S., and Milstien, S. (2003) Nat. Rev. Mol. Cell Biol. 4, 397–40714: Ogretmen, B., and Hannun, Y. A. (2004) Nat. Rev. Cancer 4, 604–61615: Holthuis, J. C., Pomorski, T., Raggers, R. J., Sprong, H., and Van Meer, G. (2001) Physiol. Rev. 81, 1689–1723

Protein Reference(s)

Database Name: UniProt

Accession number: Q9VS60

Species Accession: Human

Safety Datasheet(s) for this product:NM_Sodium Azide/wp-content/uploads/SDS/Antibody SDS with Sodium Azide Noridic-MUbio.pdf

Nordic的纯化的牛IgG可以在各种免疫测定(包括免疫扩散,免疫电泳,ELISA,Western印迹,斑点免疫结合测定(DIBA),血细胞凝集和细胞结合测定)中用作参考抗原,校准物,包被蛋白和封闭剂。该产品仅用于研究目的,并且用于体外测试,不适用于涉及人或动物的诊断或治疗程序。它可能包含有害成分。请参阅安全数据表(SDS)了解更多信息和正确的处理程序。根据当地法规处理产品残留物。此数据表的准确性尽可能合理,但Nordic-MUbio对本信息中的任何准确性或遗漏概不负责。