CD98 exits as a heterodimer containing a disulphide-linked glycosylated heavy chain and a non-glycosylated light chain. It is a member of the solute carrier family and encodes a cell surface, transmembrane protein. The protein exists as the heavy chain of a heterodimer, covalently bound through disulfide bonds to one of several possible light chains. The encoded transporter plays a role in regulation of intracellular calcium levels and transports L-type amino acids. Alternatively spliced transcript variants, encoding different isoforms, have been characterized.
Optimal dilution of the CD98 antibody should be determined by the researcher.
Native leukocytes were used as the immunogen for the CD98 antibody.
Store the CD98 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
