Heparin-binding EGF-like growth factor (HB-EGF), also called Diphtheria toxin receptor (DT-R), is a member of the EGF family of proteins that in humans is encoded by the HBEGF gene. Enables growth factor activity and heparin binding activity. Involved in several processes, including epidermal growth factor receptor signaling pathway; positive regulation of protein kinase B signaling; and positive regulation of wound healing. Located in cell surface and extracellular space. Implicated in glomerulosclerosis and perinatal necrotizing enterocolitis.
Optimal dilution of the HBEGF antibody should be determined by the researcher.
Amino acids KKRDPCLRKYKDFCIHGECKYVKE were used as the immunogen for the HBEGF antibody.
After reconstitution, the HBEGF antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
