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公司地址
苏州工业园区生物纳米园A4#216
联系电话
4000-520-616 / 18915418616
传真号码
0512-67156496
电子邮箱
info@ebiomall.com
公司网址
https://www.ebiomall.com
商品描述
Product Code
Product Name
Mouse anti P53
Size
.1 mg
Price (USD)
$310
Background
AlteRations of the p53 tumor suppressor gene are considered critical events in multistage carcinogenesis of a wide range of Human cancers. The mutations found in sporadic cancer are commonly mis-sense mutations that inactivate the tumor suppressor activity of p53. These mutant proteins are much more stable than the normal p53 protein, frequently adopt an altered conformation and accumulate within the malignant cells.
Host
Mouse
Isotype
IgG2a
Species Reactivity
Human
Product Usage
Bp53.12 reacts with a denatuRation-resistant epitope of p53. This antibody is specific for Human p53 and recognizes amino acid sequence 16-25.
Product Type
Primary Antibodies
Applications
Flow Cytometry,Immunocytochemistry,Immunohistochemistry (frozen),Immunohistochemistry (paraffin),Western blotting
Fields of Interest
Cancer, Cell Cycle
Product Source
Bp53.12 is a Mouse monoclonal IgG2a antibody derived by fusion of X63 Ag8.653 Mouse myeloma cells with spleen cells from a BALB/c Mouse immunized with recombinant Human wild-type p53 protein.
Product Formulation
Each vial contains 100 ug 1 mg/ml purified monoclonal antibody in PBS containing 0.09% sodium azide.
Storage Conditions
Store at 4
