Specificity
CAM 011-37 binds the heavy chain of human factor XII, including factor XII derivatives such as α-factor XIIa and α-factor XIIa C1-inhibitor complexes.
Immunogen
Affinity purified human factor XII.
Positive Species Reactivity
Human
Negative Species Reactivity
Not determined
Epitope Specificity
Differs from CAM 011-05.
Unit Size
200 µL: Cat. No. CAM 111-37-021 mL: Cat. No. CAM 111-37-11 mg/mL +/- 15%. See Certificate of Analysis for details.
Purification
Protein A/G purified (from culture supernatant)
Solvent
0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide
Conjugation
Unconjugated BSA free
Storage
4-8ºC without exposure to light. No precautions necessary during handling.
Target
Factor XII is a component in the coagulation cascade. It is a plasma glycoprotein that participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII to a-factor XIIa, which in turn activates factor XI to factor XIa.
bioporto的NGAL Test™是一种颗粒增强的浊度免疫测定法，用于在自动化临床化学分析仪上定量测定人尿液，EDTA血浆或肝素血浆中的与中性粒细胞明胶酶相关的脂蛋白（NGAL）。NGAL Test™校准器套件包含用于建立校准曲线的校准器解决方案。NGAL测量可用于诊断可能导致急性肾衰竭的急性肾损伤。
