Specificity
CSI 004-27 is highly specific for vitronectin. There is no evidence for cross-reactivity with other connective tissue proteins (fibronectin, elastin, collagen, laminin).
Immunogen
Lysed bovine corneal endothelial cells and extracellular matrix
Positive Species Reactivity
Bovine, Sheep (ovine)
Negative Species Reactivity
Human, Horse
Gene ID
507,525,101,119,231
Epitope Specificity
Not determined
Unit Size
200 µL: Cat. No. CSI 004-27-021 mL: Cat. No. CSI 004-27-11 mg/mL +/- 15%. See Certificate of Analysis for details.
Purification
Protein A/G purified (from culture supernatant)
Solvent
0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide
Conjugation
Unconjugated BSA free
Storage
4-8ºC without exposure to light. No precautions necessary during handling.
Target
Vitronectin is a plasma glycoprotein that circulates in the blood. Vitronectin is circulating as a mixture ofboth 75 kDa and 65 kDa forms. Vitronectin is a major cell adhesive glycoprotein and is a commoncomponent of extracellular matrix and plasma. It competes effectively with other plasma proteins and isoften involved in cell attachment, regulation of blood coagulation and immune responses. It has similartissue distribution to fibronectin and also its integrin receptor recognises fibronectin. (1)
bioporto的NGAL Test™是一种颗粒增强的浊度免疫测定法,用于在自动化临床化学分析仪上定量测定人尿液,EDTA血浆或肝素血浆中的与中性粒细胞明胶酶相关的脂蛋白(NGAL)。NGAL Test™校准器套件包含用于建立校准曲线的校准器解决方案。NGAL测量可用于诊断可能导致急性肾衰竭的急性肾损伤。