Specificity
ABS 029-01 binds human PYY. Cross-reactivity with NPY or PP in solution is <>
Immunogen
Synthetic human PYY
Positive Species Reactivity
Human
Negative Species Reactivity
Not determined
Epitope Specificity
Not determined
Unit Size
200 µL: Cat. No. ABS 029-01-021 mL: Cat. No. ABS 029-01-11 mg/mL +/- 15%. See Certificate of Analysis for details.
Purification
Protein A/G purified (from culture supernatant)
Solvent
0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide
Conjugation
Unconjugated BSA free
Storage
4-8ºC without exposure to light. No precautions necessary during handling.
Target
Peptide tyrosine-tyrosine (PYY) amide is a 36 amino acid. PYY is a member of the pancreatic polypeptide (PP) family of peptides (neuropeptide Y (NPY), PYY and PP). While NPY is localized in neurons (both in the central and peripheral nervous system) and PP in the pancreatic islets, PYY is found in both neurons and the gut. PYY is released in response to food intake from the same endocrine cells (L cells) in the intestinal mucosa as the glucagon-like peptides and inhibits gall bladder secretion, gut motility, and pancreatic secretion. These effects are similar to those of PP and overlap with the gut inhibitory activity of GLP-1.
bioporto的NGAL Test™是一种颗粒增强的浊度免疫测定法，用于在自动化临床化学分析仪上定量测定人尿液，EDTA血浆或肝素血浆中的与中性粒细胞明胶酶相关的脂蛋白（NGAL）。NGAL Test™校准器套件包含用于建立校准曲线的校准器解决方案。NGAL测量可用于诊断可能导致急性肾衰竭的急性肾损伤。
